Best Telehealth for Hormone Optimization (TRT, Sermorelin) 2026

These are our independent picks for the best US telehealth clinics specializing in hormone optimization in 2026 — testosterone replacement therapy (injectable, gel, oral), enclomiphene, sermorelin, and CJC-1295/Ipamorelin. Rankings emphasize provider specialization, lab-work inclusion, and bundled monitoring.

Affiliate disclosure: some links below are affiliate links. Editorial rankings are independent of commercial relationships. Learn more.

Our top picks

1
8.6
He & She MDBest multi-category telehealth for peptides + GLP-1
Testosterone, enclomiphene, sermorelin
From $139/moasync visit
Modern telehealth clinic offering medical weight loss (GLP-1), longevity peptides (NAD+, sermorelin, glutathione), hormone therapy, and sexual wellness. Licensed US providers; medication shipped from FDA-registered partner pharmacies.
Pros
Broad menu (GLP-1, peptides, HRT, sexual wellness)
Free shipping; medication-only billing
Ships to 49 states (excludes Louisiana for GLP-1)
Cons
No insurance billing
Sterile compounds unavailable in 10 states
Start Visit Read full review
2
8.1
Fella HealthBest GLP-1 program for men
TRT + GLP-1 combined
From $249/moasync + video visit
Men-only GLP-1 weight loss program combining medication, testosterone therapy, and behavioral coaching.
Pros
Dedicated men's metabolic protocol
Coaching + TRT integration
Strong patient outcomes
Cons
Men-only
Higher starting price than competitors
Start Visit Read full review
3
8.2
Marek HealthPerformance medicine + advanced TRT
Advanced TRT + bloodwork
From $299/movideo visit
Performance-medicine telehealth with advanced bloodwork and physician-guided hormone (TRT), peptide, and weight-loss protocols.
Pros
Performance-medicine and advanced bloodwork focus
Physician-guided hormone & peptide protocols
Strong reputation in the TRT community
Cons
Higher entry price ($299)
Coaching/lab add-ons increase total cost
Start Visit Read full review
4
8.0
Hone HealthBest for at-home TRT and hormone testing
At-home TRT testing
From $25/movideo visit
Hormone-optimization telehealth specializing in at-home testosterone testing and TRT, with weight-loss, longevity, and sexual-wellness treatments.
Pros
TRT and hormone optimization specialist
At-home lab testing included
Adds weight-loss and longevity treatments
Cons
Membership plus medication cost
State availability not fully published
Start Visit Read full review
5
8.0
MaximusMen's testosterone + enclomiphene specialist
Testosterone + enclomiphene
From $150/moasync visit
Men's hormone-optimization telehealth (testosterone, enclomiphene) plus compounded GLP-1s and growth-hormone peptides in oral, cream, and injectable formats.
Pros
Men's hormone optimization (testosterone, enclomiphene)
Compounded GLP-1 and growth-hormone peptides
Multiple delivery formats (oral, cream, injection)
Cons
Compounded only — no brand-name GLP-1
Marketing-forward, men-focused positioning
Start Visit Read full review
6
8.1
Defy MedicalVeteran TRT & hormone optimization clinic
Veteran TRT/BHRT clinic
video visit
Established hormone & TRT clinic offering bioidentical HRT, peptide therapy, sexual wellness, and GLP-1s via physician-supervised telemedicine.
Pros
Established hormone & TRT clinic with a deep menu
Bioidentical HRT, peptides, and sexual wellness
Physician-supervised phone + telemedicine
Cons
Pricing not transparent online
Concierge model can be pricey
Start Visit Read full review
7
7.8
BlokesMen's peptide + hormone optimization
Men's TRT
async + video visitBrand-name available
Data-driven men's health telehealth offering TRT, peptide therapy (sermorelin, NAD+, VIP), and FDA-approved GLP-1s, with sister brand Joi for women.
Pros
Data-driven men's hormone & peptide therapy
Peptides (sermorelin, NAD+, VIP) plus TRT
Offers FDA-approved GLP-1 medications
Cons
Lab and membership costs add up
Async-leaning provider interaction
Start Visit Read full review
8
7.8
Midi HealthBest women's midlife hormone telehealth
Best for women (midlife)
video visitBrand-name available
Women's midlife hormone-care telehealth (perimenopause/menopause) covered by insurance in all 50 states, adding GLP-1s and select peptides (CJC-1295, BPC-157).
Pros
Women's midlife hormone-care specialist
Insurance-covered visits in all 50 states
Adds GLP-1 and select peptides
Cons
Focused on perimenopause/menopause
Limited peptide menu
Start Visit Read full review
9
7.6
WinonaWomen's bioidentical HRT
Women's bioidentical HRT
async visit
Women's bioidentical HRT telehealth offering compounded estrogen, progesterone, testosterone, and sexual-wellness formulations via nationwide async care.
Pros
Women's bioidentical HRT specialist
Affordable compounded formulations
Nationwide async model
Cons
Compounded only
Limited beyond hormone & sexual wellness
Start Visit Read full review
10
7.7
Ivim HealthAffordable compounded GLP-1 + HRT
Women's HRT program
From $75/movideo visit
Compounded GLP-1 specialist (semaglutide, tirzepatide) with a women's HRT program and supplements; low $75/mo entry with video provider visits.
Pros
Compounded semaglutide & tirzepatide specialist
Low $75/mo entry plus supplements and women's HRT
Video provider visits included
Cons
Compounded only — no brand-name medications
Not available in all states
Start Visit Read full review
11
7.8
LifeMDFull-service primary care + GLP-1
From $149/moasync + video visitBrand-name available
Publicly traded full-service telehealth offering primary care, weight loss (brand-name GLP-1 + compounded), hormone therapy, and behavioral health via message and video visits nationwide.
Pros
Publicly traded; full primary-care + weight-loss menu
Both brand-name GLP-1 and compounded options
Message and video visits nationwide
Cons
Membership fee separate from medication
Upsell-heavy onboarding flow
Start Visit Read full review
12
7.5
RugietCustom compounded sexual wellness + TRT
async visit
Sexual-wellness telehealth offering customizable compounded ED formulations plus TRT and sleep support via discreet nationwide async care.
Pros
Customizable sexual-wellness formulations
Adds TRT and sleep support
Discreet nationwide async model
Cons
Pricing not shown upfront
Narrow focus outside sexual wellness
Start Visit Read full review
13
8.5
Hims & HersBest-known brand for GLP-1 and men's/women's health
From $149/moasync + video visitBrand-name available
Publicly traded telehealth platform offering FDA-approved GLP-1s (Wegovy, Zepbound, oral options), sexual wellness, hair loss, and mental health treatments for men and women under the Hims and Hers brands.
Pros
Publicly traded, established brand with a broad treatment menu
Offers FDA-approved Wegovy & Zepbound plus oral options
Bundled provider access and fast nationwide shipping
Cons
Compounded GLP-1 access was reduced in 2025
Not available in all 50 states for every treatment
Start Visit Read full review
14
7.5
FridaysHolistic GLP-1 + longevity telehealth
TRT + enclomiphene
video visitBrand-name available
Holistic telehealth combining GLP-1 weight loss (compounded + brand-name), longevity peptides (NAD+, sermorelin), and testosterone therapy via nationwide video care.
Pros
Holistic program (GLP-1, longevity, TRT)
Compounded + brand-name medication options
Nationwide video care
Cons
Compounded meds are not FDA-approved
Pricing not transparent upfront
Start Visit Read full review
15
7.6
TRT NationAffordable TRT telehealth ($99/mo)
Affordable TRT
From $99/movideo visit
Testosterone-therapy-focused telehealth also offering medical weight loss, anti-aging, and sexual health; serves most US states from $99/mo.
Pros
Affordable $99/mo TRT
Adds weight loss, anti-aging, sexual health
Telehealth across most states
Cons
Not available in AL, AK, AR, MO, HI
Compounded only
Start Visit Read full review
16
7.6
Nu Image MedicalVeteran weight loss + TRT + peptide telehealth
video visit
Established telehealth offering medical weight loss (semaglutide), TRT, sermorelin, enclomiphene, and sexual-health treatments shipped nationwide.
Pros
Long-standing telehealth brand
Weight loss, TRT, and sermorelin
Nationwide shipping
Cons
Compounded only
Pricing not transparent upfront
Start Visit Read full review
17
7.6
Valhalla VitalityMulti-category hormone + longevity telehealth
async + video visit
Multi-category telehealth offering weight loss, TRT/hormone health, NAD+ and longevity therapy, sexual health, and peptide-based wellness.
Pros
Broad menu (weight loss, TRT, NAD+, sexual health)
Longevity and peptide focus
Message + video care
Cons
Compounded only
Pricing not transparent upfront
Start Visit Read full review
18
7.5
BodyLogicMDBioidentical HRT practitioner network
Bioidentical HRT
From $79/movideo visit
National network of bioidentical-hormone and functional-medicine practitioners offering HRT, weight loss, sexual health, and supplements via telehealth and in-person visits from $79.
Pros
Established bioidentical-HRT network
Functional-medicine approach
Telehealth + in-person options
Cons
Practitioner quality varies by location
Concierge-style pricing
Start Visit Read full review
19
7.5
Elite HRTTRT, NAD+ & peptide therapy (50 states)
From $325/movideo visit
Hormone-optimization and longevity telehealth offering TRT, HGH/sermorelin, NAD+, and peptide therapy across all 50 states.
Pros
TRT plus NAD+ and peptides
Available in all 50 states
Dedicated wellness concierge
Cons
Higher $325 entry
Compounded only
Start Visit Read full review
20
7.5
Ways2WellBloodwork-driven hormone + peptide therapy
video visit
Data-driven telehealth using comprehensive bloodwork to guide hormone optimization, peptide therapy (BPC-157, sermorelin), longevity, and regenerative treatments.
Pros
Comprehensive bloodwork-led protocols
Peptide and hormone optimization
Longevity-focused care
Cons
Available in only 6 states
Pricing not transparent upfront
Start Visit Read full review
21
7.4
GenemedicsHormone optimization + anti-aging medicine
video visit
Physician-led hormone-optimization and anti-aging telehealth offering TRT, HRT for men and women, peptides, and medical weight loss with comprehensive lab work.
Pros
Physician-led hormone optimization
Men's and women's HRT + peptides
Comprehensive lab work
Cons
Pricing not transparent upfront
Compounded only
Start Visit Read full review
22
7.5
AlphaMDBudget TRT + sermorelin telehealth
Budget TRT
From $98/movideo visit
Men's and women's TRT telehealth offering testosterone, HCG, enclomiphene, sermorelin, and male-enhancement treatments from $98/mo.
Pros
Affordable $98/mo TRT
Male and female hormone therapy
Adds sermorelin and HCG
Cons
Compounded only
Smaller brand footprint
Start Visit Read full review
23
7.3
Kingsberg MedicalGH peptide + TRT therapy
From $200/moasync visit
Hormone and growth-hormone therapy telehealth offering TRT, sermorelin/GH peptides, and semaglutide weight loss nationwide.
Pros
Growth-hormone and sermorelin focus
TRT and weight loss options
Nationwide telehealth
Cons
Wide price range ($200-$1000/mo)
Compounded only
Start Visit Read full review
24
7.6
AlloyWomen's menopause HRT + GLP-1
Women's menopause
async visitBrand-name available
Women's midlife telehealth offering menopause HRT, weight care (brand-name + compounded GLP-1), sexual health, and skincare via async messaging.
Pros
Menopause-expert clinicians
Brand-name + compounded GLP-1 weight care
Sexual-health and skincare add-ons
Cons
Async-only provider model
Pricing not transparent upfront
Start Visit Read full review
25
7.5
EvernowWomen's menopause HRT telehealth
Women's menopause
From $35/movideo visit
Women's menopause and perimenopause telehealth offering estrogen, progesterone, and related HRT with video and messaging care nationwide from $35/mo.
Pros
Menopause-specialist clinicians
Affordable $35/mo entry
Video + messaging care nationwide
Cons
Menopause/HRT focus only
No peptide offerings
Start Visit Read full review
26
7.4
GennevOB/GYN-led menopause telehealth
OB/GYN menopause
video visit
Menopause-specialist telehealth (OB/GYNs and dietitians) offering HRT and symptom management via video visits nationwide.
Pros
OB/GYN menopause specialists
Dietitian and coaching support
Nationwide video visits
Cons
Menopause focus only
No peptide offerings
Start Visit Read full review
27
7.4
WispWomen's sexual & reproductive health
async + video visit
Women's sexual and reproductive health telehealth (BV, UTI, birth control, herpes) expanding into menopause care, PCOS, and longevity, nationwide.
Pros
Fast women's sexual-health prescriptions
Menopause and PCOS care added
Nationwide discreet delivery
Cons
Reproductive-health focus
Limited peptide offerings
Start Visit Read full review
28
7.4
10X Health SystemGenetic-testing-led peptides & NAD+
video visit
Wellness-and-longevity brand offering genetic testing, peptides, NAD+ therapy, IV drips, and personalized supplement protocols via advisors and select clinics.
Pros
Popular genetic-testing-led protocols
Peptides, NAD+, and IV therapy
Personalized supplement plans
Cons
Wellness/supplement-heavy positioning
Limited physical locations
Start Visit Read full review
29
7.6
REX MDMen's health: ED + GLP-1 + TRT
async + video visit
Men's health telehealth offering ED treatments, GLP-1 weight loss (semaglutide), testosterone therapy, hair growth, and sleep support nationwide.
Pros
Broad men's health menu
GLP-1 weight loss + TRT + ED
Nationwide async + video care
Cons
Compounded GLP-1 focus
Membership/visit fees apply
Start Visit Read full review
30
7.7
Joi Women's WellnessWomen's peptide + hormone optimization
Women's HRT
async + video visitBrand-name available
Women's hormone-optimization telehealth (sister brand to Blokes) offering HRT, peptide therapy (sermorelin, NAD+), GLP-1 weight loss, and sexual wellness.
Pros
Women-focused hormone and peptide therapy
Sermorelin, NAD+, and GLP-1 options
Data-driven lab-led protocols
Cons
Lab and membership costs add up
Async-leaning provider interaction
Start Visit Read full review
31
7.4
Renew YouthComprehensive age-management telehealth
video visit
Comprehensive age-management telehealth offering TRT, women's HRT, thyroid/adrenal therapy, sexual health, weight loss, and longevity treatments.
Pros
Broad age-management menu
Men's and women's hormone therapy
Longevity and weight-loss options
Cons
Pricing not transparent upfront
Compounded only
Start Visit Read full review
32
7.4
Circle MedicalInsurance-accepted primary care + GLP-1
Testosterone therapy
video visit
UCSF-affiliated telehealth primary care offering GLP-1 weight management, testosterone therapy, and insurance-accepted video visits.
Pros
Insurance-accepted primary care
GLP-1 and testosterone therapy
UCSF-affiliated clinicians
Cons
Video-visit primary-care model
Limited peptide menu
Start Visit Read full review
33
7.3
Elektra HealthMenopause education + HRT telehealth
Women's menopause
video visit
Menopause-specialist telehealth offering hormonal and non-hormonal treatments plus 1:1 support and education for perimenopause and menopause.
Pros
Dedicated menopause specialists
Hormonal + non-hormonal options
Education and 1:1 support
Cons
Menopause focus only
No peptide offerings
Start Visit Read full review
34
7.2
Pandia HealthWomen's birth control + menopause HRT
Women's menopause
video visit
Women-founded telehealth for birth control and menopausal hormone therapy with online doctor consults across 14 states.
Pros
Women-founded birth control + menopause HRT
Free delivery and auto-refills
Doctor-led online consults
Cons
Available in 14 states
No peptide offerings
Start Visit Read full review
35
7.6
PeterMDMen's TRT + peptide + GLP-1 telehealth
Men's TRT
video visit
Men's health and longevity telehealth offering testosterone therapy, sermorelin, NAD+, and GLP-1 weight loss nationwide.
Pros
TRT, sermorelin, and NAD+
GLP-1 weight loss included
Nationwide video care
Cons
Compounded only
Pricing not transparent upfront
Start Visit Read full review
36
7.4
Nava HealthIntegrative longevity + peptide telehealth
video visit
Integrative and longevity telehealth (with mid-Atlantic centers) offering hormone optimization, peptide therapy, NAD+, and medical weight loss via virtual and in-person care.
Pros
Integrative longevity medicine
Hormone, peptide, and NAD+ therapy
Virtual + in-person options
Cons
In-person centers concentrated regionally
Pricing not transparent upfront
Start Visit Read full review

Frequently asked questions

What is the best TRT telehealth in 2026?

For men combining TRT with metabolic care, Fella Health is the top integrated option (TRT + GLP-1 + coaching). For a broader menu (testosterone in three formats plus enclomiphene plus sermorelin), He & She MD is the best multi-category provider.

Do telehealth TRT clinics require blood work?

Reputable telehealth TRT providers require baseline lab work (total and free testosterone, estradiol, hematocrit, PSA, CBC, CMP) before prescribing, and follow-up labs at 6–12 weeks and then every 6–12 months. Some providers include lab work in the monthly cost; others bill it separately.

Is sermorelin a legal growth-hormone alternative?

Sermorelin is an FDA-approved (now discontinued for brand-name distribution) growth-hormone-releasing hormone (GHRH) analog. Because it is a component of an approved drug, it can be legally compounded by 503A pharmacies under individual prescriptions. It is widely prescribed by US telehealth clinics today.

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