Best Telehealth for Hormone Optimization (TRT, Sermorelin) 2026
These are our independent picks for the best US telehealth clinics specializing in hormone optimization in 2026 — testosterone replacement therapy (injectable, gel, oral), enclomiphene, sermorelin, and CJC-1295/Ipamorelin. Rankings emphasize provider specialization, lab-work inclusion, and bundled monitoring.
Affiliate disclosure: some links below are affiliate links. Editorial rankings are independent of commercial relationships. Learn more.
Our top picks
- 18.6He & She MDBest multi-category telehealth for peptides + GLP-1
Testosterone, enclomiphene, sermorelin
From $139/moasync visitModern telehealth clinic offering medical weight loss (GLP-1), longevity peptides (NAD+, sermorelin, glutathione), hormone therapy, and sexual wellness. Licensed US providers; medication shipped from FDA-registered partner pharmacies.
Pros
- Broad menu (GLP-1, peptides, HRT, sexual wellness)
- Free shipping; medication-only billing
- Ships to 49 states (excludes Louisiana for GLP-1)
Cons
- No insurance billing
- Sterile compounds unavailable in 10 states
- 28.1Fella HealthBest GLP-1 program for men
TRT + GLP-1 combined
From $249/moasync + video visitMen-only GLP-1 weight loss program combining medication, testosterone therapy, and behavioral coaching.
Pros
- Dedicated men's metabolic protocol
- Coaching + TRT integration
- Strong patient outcomes
Cons
- Men-only
- Higher starting price than competitors
- 38.2Marek HealthPerformance medicine + advanced TRT
Advanced TRT + bloodwork
From $299/movideo visitPerformance-medicine telehealth with advanced bloodwork and physician-guided hormone (TRT), peptide, and weight-loss protocols.
Pros
- Performance-medicine and advanced bloodwork focus
- Physician-guided hormone & peptide protocols
- Strong reputation in the TRT community
Cons
- Higher entry price ($299)
- Coaching/lab add-ons increase total cost
- 48.0Hone HealthBest for at-home TRT and hormone testing
At-home TRT testing
From $25/movideo visitHormone-optimization telehealth specializing in at-home testosterone testing and TRT, with weight-loss, longevity, and sexual-wellness treatments.
Pros
- TRT and hormone optimization specialist
- At-home lab testing included
- Adds weight-loss and longevity treatments
Cons
- Membership plus medication cost
- State availability not fully published
- 58.0MaximusMen's testosterone + enclomiphene specialist
Testosterone + enclomiphene
From $150/moasync visitMen's hormone-optimization telehealth (testosterone, enclomiphene) plus compounded GLP-1s and growth-hormone peptides in oral, cream, and injectable formats.
Pros
- Men's hormone optimization (testosterone, enclomiphene)
- Compounded GLP-1 and growth-hormone peptides
- Multiple delivery formats (oral, cream, injection)
Cons
- Compounded only — no brand-name GLP-1
- Marketing-forward, men-focused positioning
- 68.1Defy MedicalVeteran TRT & hormone optimization clinic
Veteran TRT/BHRT clinic
video visitEstablished hormone & TRT clinic offering bioidentical HRT, peptide therapy, sexual wellness, and GLP-1s via physician-supervised telemedicine.
Pros
- Established hormone & TRT clinic with a deep menu
- Bioidentical HRT, peptides, and sexual wellness
- Physician-supervised phone + telemedicine
Cons
- Pricing not transparent online
- Concierge model can be pricey
- 77.8BlokesMen's peptide + hormone optimization
Men's TRT
async + video visitBrand-name availableData-driven men's health telehealth offering TRT, peptide therapy (sermorelin, NAD+, VIP), and FDA-approved GLP-1s, with sister brand Joi for women.
Pros
- Data-driven men's hormone & peptide therapy
- Peptides (sermorelin, NAD+, VIP) plus TRT
- Offers FDA-approved GLP-1 medications
Cons
- Lab and membership costs add up
- Async-leaning provider interaction
- 87.8Midi HealthBest women's midlife hormone telehealth
Best for women (midlife)
video visitBrand-name availableWomen's midlife hormone-care telehealth (perimenopause/menopause) covered by insurance in all 50 states, adding GLP-1s and select peptides (CJC-1295, BPC-157).
Pros
- Women's midlife hormone-care specialist
- Insurance-covered visits in all 50 states
- Adds GLP-1 and select peptides
Cons
- Focused on perimenopause/menopause
- Limited peptide menu
- 97.6WinonaWomen's bioidentical HRT
Women's bioidentical HRT
async visitWomen's bioidentical HRT telehealth offering compounded estrogen, progesterone, testosterone, and sexual-wellness formulations via nationwide async care.
Pros
- Women's bioidentical HRT specialist
- Affordable compounded formulations
- Nationwide async model
Cons
- Compounded only
- Limited beyond hormone & sexual wellness
- 107.7Ivim HealthAffordable compounded GLP-1 + HRT
Women's HRT program
From $75/movideo visitCompounded GLP-1 specialist (semaglutide, tirzepatide) with a women's HRT program and supplements; low $75/mo entry with video provider visits.
Pros
- Compounded semaglutide & tirzepatide specialist
- Low $75/mo entry plus supplements and women's HRT
- Video provider visits included
Cons
- Compounded only — no brand-name medications
- Not available in all states
- 117.8LifeMDFull-service primary care + GLP-1From $149/moasync + video visitBrand-name available
Publicly traded full-service telehealth offering primary care, weight loss (brand-name GLP-1 + compounded), hormone therapy, and behavioral health via message and video visits nationwide.
Pros
- Publicly traded; full primary-care + weight-loss menu
- Both brand-name GLP-1 and compounded options
- Message and video visits nationwide
Cons
- Membership fee separate from medication
- Upsell-heavy onboarding flow
- 127.5RugietCustom compounded sexual wellness + TRTasync visit
Sexual-wellness telehealth offering customizable compounded ED formulations plus TRT and sleep support via discreet nationwide async care.
Pros
- Customizable sexual-wellness formulations
- Adds TRT and sleep support
- Discreet nationwide async model
Cons
- Pricing not shown upfront
- Narrow focus outside sexual wellness
- 138.5Hims & HersBest-known brand for GLP-1 and men's/women's healthFrom $149/moasync + video visitBrand-name available
Publicly traded telehealth platform offering FDA-approved GLP-1s (Wegovy, Zepbound, oral options), sexual wellness, hair loss, and mental health treatments for men and women under the Hims and Hers brands.
Pros
- Publicly traded, established brand with a broad treatment menu
- Offers FDA-approved Wegovy & Zepbound plus oral options
- Bundled provider access and fast nationwide shipping
Cons
- Compounded GLP-1 access was reduced in 2025
- Not available in all 50 states for every treatment
- 147.5FridaysHolistic GLP-1 + longevity telehealth
TRT + enclomiphene
video visitBrand-name availableHolistic telehealth combining GLP-1 weight loss (compounded + brand-name), longevity peptides (NAD+, sermorelin), and testosterone therapy via nationwide video care.
Pros
- Holistic program (GLP-1, longevity, TRT)
- Compounded + brand-name medication options
- Nationwide video care
Cons
- Compounded meds are not FDA-approved
- Pricing not transparent upfront
- 157.6TRT NationAffordable TRT telehealth ($99/mo)
Affordable TRT
From $99/movideo visitTestosterone-therapy-focused telehealth also offering medical weight loss, anti-aging, and sexual health; serves most US states from $99/mo.
Pros
- Affordable $99/mo TRT
- Adds weight loss, anti-aging, sexual health
- Telehealth across most states
Cons
- Not available in AL, AK, AR, MO, HI
- Compounded only
- 167.6Nu Image MedicalVeteran weight loss + TRT + peptide telehealthvideo visit
Established telehealth offering medical weight loss (semaglutide), TRT, sermorelin, enclomiphene, and sexual-health treatments shipped nationwide.
Pros
- Long-standing telehealth brand
- Weight loss, TRT, and sermorelin
- Nationwide shipping
Cons
- Compounded only
- Pricing not transparent upfront
- 177.6Valhalla VitalityMulti-category hormone + longevity telehealthasync + video visit
Multi-category telehealth offering weight loss, TRT/hormone health, NAD+ and longevity therapy, sexual health, and peptide-based wellness.
Pros
- Broad menu (weight loss, TRT, NAD+, sexual health)
- Longevity and peptide focus
- Message + video care
Cons
- Compounded only
- Pricing not transparent upfront
- 187.5BodyLogicMDBioidentical HRT practitioner network
Bioidentical HRT
From $79/movideo visitNational network of bioidentical-hormone and functional-medicine practitioners offering HRT, weight loss, sexual health, and supplements via telehealth and in-person visits from $79.
Pros
- Established bioidentical-HRT network
- Functional-medicine approach
- Telehealth + in-person options
Cons
- Practitioner quality varies by location
- Concierge-style pricing
- 197.5Elite HRTTRT, NAD+ & peptide therapy (50 states)From $325/movideo visit
Hormone-optimization and longevity telehealth offering TRT, HGH/sermorelin, NAD+, and peptide therapy across all 50 states.
Pros
- TRT plus NAD+ and peptides
- Available in all 50 states
- Dedicated wellness concierge
Cons
- Higher $325 entry
- Compounded only
- 207.5Ways2WellBloodwork-driven hormone + peptide therapyvideo visit
Data-driven telehealth using comprehensive bloodwork to guide hormone optimization, peptide therapy (BPC-157, sermorelin), longevity, and regenerative treatments.
Pros
- Comprehensive bloodwork-led protocols
- Peptide and hormone optimization
- Longevity-focused care
Cons
- Available in only 6 states
- Pricing not transparent upfront
- 217.4GenemedicsHormone optimization + anti-aging medicinevideo visit
Physician-led hormone-optimization and anti-aging telehealth offering TRT, HRT for men and women, peptides, and medical weight loss with comprehensive lab work.
Pros
- Physician-led hormone optimization
- Men's and women's HRT + peptides
- Comprehensive lab work
Cons
- Pricing not transparent upfront
- Compounded only
- 227.5AlphaMDBudget TRT + sermorelin telehealth
Budget TRT
From $98/movideo visitMen's and women's TRT telehealth offering testosterone, HCG, enclomiphene, sermorelin, and male-enhancement treatments from $98/mo.
Pros
- Affordable $98/mo TRT
- Male and female hormone therapy
- Adds sermorelin and HCG
Cons
- Compounded only
- Smaller brand footprint
- 237.3Kingsberg MedicalGH peptide + TRT therapyFrom $200/moasync visit
Hormone and growth-hormone therapy telehealth offering TRT, sermorelin/GH peptides, and semaglutide weight loss nationwide.
Pros
- Growth-hormone and sermorelin focus
- TRT and weight loss options
- Nationwide telehealth
Cons
- Wide price range ($200-$1000/mo)
- Compounded only
- 247.6AlloyWomen's menopause HRT + GLP-1
Women's menopause
async visitBrand-name availableWomen's midlife telehealth offering menopause HRT, weight care (brand-name + compounded GLP-1), sexual health, and skincare via async messaging.
Pros
- Menopause-expert clinicians
- Brand-name + compounded GLP-1 weight care
- Sexual-health and skincare add-ons
Cons
- Async-only provider model
- Pricing not transparent upfront
- 257.5EvernowWomen's menopause HRT telehealth
Women's menopause
From $35/movideo visitWomen's menopause and perimenopause telehealth offering estrogen, progesterone, and related HRT with video and messaging care nationwide from $35/mo.
Pros
- Menopause-specialist clinicians
- Affordable $35/mo entry
- Video + messaging care nationwide
Cons
- Menopause/HRT focus only
- No peptide offerings
- 267.4GennevOB/GYN-led menopause telehealth
OB/GYN menopause
video visitMenopause-specialist telehealth (OB/GYNs and dietitians) offering HRT and symptom management via video visits nationwide.
Pros
- OB/GYN menopause specialists
- Dietitian and coaching support
- Nationwide video visits
Cons
- Menopause focus only
- No peptide offerings
- 277.4WispWomen's sexual & reproductive healthasync + video visit
Women's sexual and reproductive health telehealth (BV, UTI, birth control, herpes) expanding into menopause care, PCOS, and longevity, nationwide.
Pros
- Fast women's sexual-health prescriptions
- Menopause and PCOS care added
- Nationwide discreet delivery
Cons
- Reproductive-health focus
- Limited peptide offerings
- 287.410X Health SystemGenetic-testing-led peptides & NAD+video visit
Wellness-and-longevity brand offering genetic testing, peptides, NAD+ therapy, IV drips, and personalized supplement protocols via advisors and select clinics.
Pros
- Popular genetic-testing-led protocols
- Peptides, NAD+, and IV therapy
- Personalized supplement plans
Cons
- Wellness/supplement-heavy positioning
- Limited physical locations
- 297.6REX MDMen's health: ED + GLP-1 + TRTasync + video visit
Men's health telehealth offering ED treatments, GLP-1 weight loss (semaglutide), testosterone therapy, hair growth, and sleep support nationwide.
Pros
- Broad men's health menu
- GLP-1 weight loss + TRT + ED
- Nationwide async + video care
Cons
- Compounded GLP-1 focus
- Membership/visit fees apply
- 307.7Joi Women's WellnessWomen's peptide + hormone optimization
Women's HRT
async + video visitBrand-name availableWomen's hormone-optimization telehealth (sister brand to Blokes) offering HRT, peptide therapy (sermorelin, NAD+), GLP-1 weight loss, and sexual wellness.
Pros
- Women-focused hormone and peptide therapy
- Sermorelin, NAD+, and GLP-1 options
- Data-driven lab-led protocols
Cons
- Lab and membership costs add up
- Async-leaning provider interaction
- 317.4Renew YouthComprehensive age-management telehealthvideo visit
Comprehensive age-management telehealth offering TRT, women's HRT, thyroid/adrenal therapy, sexual health, weight loss, and longevity treatments.
Pros
- Broad age-management menu
- Men's and women's hormone therapy
- Longevity and weight-loss options
Cons
- Pricing not transparent upfront
- Compounded only
- 327.4Circle MedicalInsurance-accepted primary care + GLP-1
Testosterone therapy
video visitUCSF-affiliated telehealth primary care offering GLP-1 weight management, testosterone therapy, and insurance-accepted video visits.
Pros
- Insurance-accepted primary care
- GLP-1 and testosterone therapy
- UCSF-affiliated clinicians
Cons
- Video-visit primary-care model
- Limited peptide menu
- 337.3Elektra HealthMenopause education + HRT telehealth
Women's menopause
video visitMenopause-specialist telehealth offering hormonal and non-hormonal treatments plus 1:1 support and education for perimenopause and menopause.
Pros
- Dedicated menopause specialists
- Hormonal + non-hormonal options
- Education and 1:1 support
Cons
- Menopause focus only
- No peptide offerings
- 347.2Pandia HealthWomen's birth control + menopause HRT
Women's menopause
video visitWomen-founded telehealth for birth control and menopausal hormone therapy with online doctor consults across 14 states.
Pros
- Women-founded birth control + menopause HRT
- Free delivery and auto-refills
- Doctor-led online consults
Cons
- Available in 14 states
- No peptide offerings
- 357.6PeterMDMen's TRT + peptide + GLP-1 telehealth
Men's TRT
video visitMen's health and longevity telehealth offering testosterone therapy, sermorelin, NAD+, and GLP-1 weight loss nationwide.
Pros
- TRT, sermorelin, and NAD+
- GLP-1 weight loss included
- Nationwide video care
Cons
- Compounded only
- Pricing not transparent upfront
- 367.4Nava HealthIntegrative longevity + peptide telehealthvideo visit
Integrative and longevity telehealth (with mid-Atlantic centers) offering hormone optimization, peptide therapy, NAD+, and medical weight loss via virtual and in-person care.
Pros
- Integrative longevity medicine
- Hormone, peptide, and NAD+ therapy
- Virtual + in-person options
Cons
- In-person centers concentrated regionally
- Pricing not transparent upfront
- 378.0FrontCareFlat pricing on compounded GLP-1s
TRT and HRT at flat prices
From $133/moasync visitCash-pay telehealth platform where licensed US doctors prescribe compounded GLP-1s (injectable and oral-drop semaglutide and tirzepatide) plus peptides such as BPC-157, TB-500, CJC-1295/Ipamorelin, MOTS-c, tesamorelin, sermorelin and NAD+. One flat monthly price for any dose.
Pros
- One price for any dose, no membership fee
- Free doctor consult and free shipping
- Wide menu: GLP-1s plus recovery and longevity peptides
- Automatic refund if not medically approved
Cons
- Compounded only, no brand-name Wegovy or Zepbound
- Not available in Alabama, Mississippi or Alaska
- Newer brand with few public reviews
Frequently asked questions
What is the best TRT telehealth in 2026?
For men combining TRT with metabolic care, Fella Health is the top integrated option (TRT + GLP-1 + coaching). For a broader menu (testosterone in three formats plus enclomiphene plus sermorelin), He & She MD is the best multi-category provider.
Do telehealth TRT clinics require blood work?
Reputable telehealth TRT providers require baseline lab work (total and free testosterone, estradiol, hematocrit, PSA, CBC, CMP) before prescribing, and follow-up labs at 6–12 weeks and then every 6–12 months. Some providers include lab work in the monthly cost; others bill it separately.
Is sermorelin a legal growth-hormone alternative?
Sermorelin is an FDA-approved (now discontinued for brand-name distribution) growth-hormone-releasing hormone (GHRH) analog. Because it is a component of an approved drug, it can be legally compounded by 503A pharmacies under individual prescriptions. It is widely prescribed by US telehealth clinics today.
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