Overview
BPC-157 (Body Protection Compound-157) is a synthetic 15-amino-acid peptide derived from a protein found in gastric juice. It has been widely discussed in fitness, wellness, and longevity circles for its purported benefits for tendon and ligament healing, gut health, and tissue repair. Despite strong interest and a large body of animal and preclinical research, BPC-157 has never been approved by the FDA for any use. In the United States, it is prohibited for compounding and has been the subject of federal enforcement. Understanding both the science and the regulatory reality is important for anyone considering or researching this compound.
People are drawn to BPC-157 because of claims about faster recovery from injury, improved gut function, and anti-inflammatory effects. It is critical to recognize that these claims are not supported by completed human trials and that obtaining or prescribing BPC-157 in the US for human use puts patients and providers at legal and safety risk. This page explains what BPC-157 is, what the evidence shows, and why the regulatory status matters.
How It Works (Mechanism of Action)
In animal and cell studies, BPC-157 has been linked to processes involved in angiogenesis (formation of new blood vessels), tendon and ligament healing, and gut mucosal repair. It is thought to modulate growth hormone receptors and other signaling pathways that support tissue repair. Because there are no approved human studies, the exact mechanism in people is not established, and dosing and safety in humans are unknown.


