Advanced Peptides Inc has operated as a contract research organization in Boston, MA since 2007, providing custom peptide synthesis and biologics development services to biotechnology companies, pharmaceutical researchers, and academic institutions. The company specializes in manufacturing peptides ranging from milligram to multi-gram scale, supporting clients from early discovery through preclinical and clinical development phases. Their Boston facility houses solid-phase and liquid-phase synthesis capabilities, enabling production of complex sequences including those with non-natural amino acids, cyclizations, and post-translational modifications.
The core service portfolio includes custom peptide synthesis with purity specifications from crude to greater than 98% HPLC, peptide library construction for screening applications, and process development for peptides advancing toward GMP manufacturing. Advanced Peptides Inc synthesizes therapeutic peptides, diagnostic peptides, and research-grade compounds across multiple therapeutic areas including oncology, metabolic disorders, and immunology. The company maintains analytical capabilities including mass spectrometry, HPLC, amino acid analysis, and peptide sequencing to verify identity and purity of all synthesized products. Their peptide library services encompass positional scanning libraries, alanine scan libraries, and custom arrays designed to client specifications for epitope mapping and lead optimization studies.
The scientific team at Advanced Peptides Inc includes PhD-level chemists with expertise in peptide chemistry, medicinal chemistry, and bioconjugation techniques. Project management follows a structured timeline approach with defined milestones for synthesis, purification, and quality control testing. Clients receive detailed analytical reports including HPLC chromatograms, mass spectrometry data, and certificates of analysis with each peptide delivery. The company has supported over 400 biotech and pharmaceutical clients since its founding, manufacturing peptides for research programs that have advanced into clinical trials.
Advanced Peptides Inc operates under ISO 9001:2015 quality management standards, with documented procedures for synthesis, purification, and testing protocols. The Boston location provides access to the region's concentrated biotechnology ecosystem, facilitating collaboration with local research institutions and emerging biotech companies. Turnaround times range from two to eight weeks depending on peptide length, complexity, and quantity requirements. The company offers consultation services to help clients optimize peptide sequences for synthesis feasibility, stability, and scalability considerations before initiating production.
For biologics development, Advanced Peptides Inc provides peptide-protein conjugation services, peptide antigen design for antibody generation, and custom peptide modification including PEGylation, acetylation, and phosphorylation. Their capabilities extend to difficult sequences containing multiple cysteine residues requiring orthogonal protection strategies, D-amino acids, and beta-amino acids. The company maintains confidentiality agreements with all clients and implements secure data management systems for proprietary sequence information. Technical support includes troubleshooting synthesis challenges, recommending purification strategies, and advising on storage conditions to maintain peptide stability during shipping and long-term storage.
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