


Angela D. Liddell, CRNA, operates a functional medicine practice in Sioux Falls, South Dakota, focusing on hormone optimization, metabolic restoration, and gut health through evidence-based regenerative therapies. As a Certified Registered Nurse Anesthetist with board certification from the American Board of Anti-Aging and Regenerative Medicine (ABAAHP), Angela brings clinical precision and advanced training to her approach in addressing the root causes of metabolic dysfunction, hormonal imbalances, and chronic inflammation. Her practice serves patients throughout the Sioux Falls metro area and across South Dakota seeking alternatives to conventional symptom management.
Angela D. Liddell, CRNA offers a range of peptide therapy options tailored to individual patient needs. Treatment protocols are customized based on health goals, lab work, and medical history, with options for hormone optimization, metabolic health, tissue repair, and performance enhancement.
Angela's clinical background as a CRNA informs her meticulous approach to patient safety, medication interactions, and physiological monitoring throughout treatment. Her ABAAHP certification reflects specialized training in hormone replacement therapy, nutrient optimization, and regenerative medicine protocols that extend beyond standard medical education. Patients work directly with Angela for initial consultations, ongoing adjustments, and clinical oversight, ensuring continuity of care and personalized attention throughout their treatment journey. Her practice emphasizes education, helping patients understand the mechanisms behind their symptoms and the scientific rationale for each intervention.
New patients in Sioux Falls begin with a comprehensive intake that includes detailed health history, symptom assessment, and laboratory testing to establish baseline hormone levels, metabolic markers, inflammatory indicators, and nutrient status. Angela reviews results in a follow-up consultation, explaining findings and proposing a treatment plan that may combine peptide therapy with bioidentical hormone replacement, targeted supplementation, or dietary modifications. Patients receive clear instructions on peptide administration, expected timelines for results, and protocols for monitoring progress through symptom tracking and follow-up labs. The practice maintains regular communication channels for questions and adjustments as treatment progresses.
For patients unable to visit the Sioux Falls office in person, Angela offers telehealth consultations for established patients and select new patient evaluations, expanding access to her expertise across rural South Dakota communities. This virtual care option includes lab coordination through local facilities, prescription management through partnered pharmacies, and video follow-ups to assess progress and refine protocols. Whether addressing chronic fatigue linked to hormonal decline, metabolic syndrome resistant to diet and exercise alone, or gut dysfunction contributing to systemic inflammation, Angela's practice provides South Dakota residents with access to regenerative medicine approaches grounded in clinical experience and functional medicine principles.
Angela D. Liddell· CRNA, ABAAHP
Angela D. Liddell, CRNA, ABAAHP
Chief Executive Officer, Functional Wellness and Integrative Pain Management Specialist
Helping individuals of all ages optimize their healthspan and vitality through personalized, root-cause care. Angela specializes in hormone balance, metabolic health, gut optimization, and regenerative therapies—delivering precision diagnostics and concierge-level functional medicine with a focus on long-term wellness, men’s and women’s health, and integrative pain management.
Kimberly Dewing, PA-C
Expert in Integrative Dermatology & Functional Medicine
Kim brings years of experience in dermatology, women’s health and urogynecology, and is widely known for her compassionate, thoughtful approach to patient care. She is especially passionate about helping women navigate hormonal health, skin conditions, and fertility concerns with personalized, root-cause solutions.
Douglass Ngnotchue, Medical Office Assistant & Phlebotomist
Functional Medicine
Longevity Medicine
Bioidentical Hormone Replacement Therapy
Advanced Gut Health Care
Advanced Thyroid Care
GLP-1 Assisted Weight Loss
Sexual Health & Hormone Optimization
Genetic Testing & Early Cancer Screening
PRPx™: Advanced Platelet-Rich Plasma Therapy
Peptide Therapy
IV Therapy
Integrative Dermatology
Wrinkle Relaxers (Injectables)
Therapeutic Supplement Programs
Customized Probiotic Therapies
+2 more services — contact clinic for full list
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