


Clinic 45 operates as an independent medical spa in Houston, Texas, where Dr. Joseph E. Sleiman, M.D., directs a practice centered on medical weight loss, bariatric medicine, and aesthetic services. The clinic integrates internal medicine expertise with non-surgical body contouring and pharmacotherapy-based weight management programs designed for patients seeking alternatives to bariatric surgery. Dr. Sleiman's background in internal medicine informs the clinic's approach to obesity prevention and metabolic health, positioning Clinic 45 as a resource for Houston-area patients requiring physician-supervised weight loss protocols that address underlying health conditions alongside aesthetic goals.
The clinic's weight loss programs incorporate GLP-1 receptor agonists including semaglutide and tirzepatide, which Dr. Sleiman prescribes as part of comprehensive treatment plans that may also include phentermine for appetite suppression and vitamin B12 supplementation to support energy levels during caloric restriction. Clinic 45 offers structured ketogenic diet programs with ongoing monitoring, combining macronutrient guidance with regular lab work to track metabolic markers and adjust treatment protocols. Non-surgical fat reduction modalities complement pharmacological interventions, allowing patients to target localized adipose deposits while systemic weight loss progresses. The clinic's aesthetic medicine services extend to body contouring procedures that refine results achieved through diet, medication, and lifestyle modification, creating a continuum of care from initial weight loss through maintenance and cosmetic enhancement.
Dr. Sleiman's medical oversight ensures that weight loss interventions account for comorbid conditions common in patients with obesity, including hypertension, dyslipidemia, and insulin resistance. The clinic's internal medicine foundation allows for management of these conditions concurrently with weight reduction efforts, with Dr. Sleiman adjusting medications and monitoring cardiovascular and metabolic parameters throughout treatment. Nursing staff at Clinic 45 administer injections, perform body composition assessments, and provide patient education on medication protocols and dietary adherence. The clinic's pharmacy coordination streamlines access to prescribed medications, with staff assisting patients in navigating insurance coverage for GLP-1 agonists and compounded formulations when commercially available products present cost barriers.
Patients at Clinic 45 typically begin with an initial consultation that includes comprehensive lab work to establish baseline metabolic function, hormone levels, and nutritional status. Dr. Sleiman reviews results during follow-up visits, which may occur in-person at the Houston clinic or via video consultation for established patients requiring medication adjustments or progress monitoring. The hybrid consultation model accommodates patients across the greater Houston metropolitan area, with telehealth appointments available exclusively for Texas residents in compliance with state medical practice regulations. In-office visits allow for procedures such as lipotropic injections, body measurements, and aesthetic treatments that cannot be delivered remotely, while virtual check-ins support medication management and dietary counseling between in-person appointments.
Clinic 45 distinguishes itself through Dr. Sleiman's integration of bariatric medicine principles within a medical spa environment, offering patients access to prescription weight loss medications and physician supervision without requiring referral to hospital-based bariatric programs. The clinic's focus on ketogenic diet implementation provides structured support for patients pursuing low-carbohydrate approaches, with protocols that include ketone monitoring and electrolyte management to prevent common complications of nutritional ketosis. Patients seeking aesthetic refinement following significant weight loss can transition seamlessly to body contouring services within the same practice, maintaining continuity of care under Dr. Sleiman's direction. The clinic's location in Houston positions it to serve a diverse patient population seeking culturally informed care and Spanish-language support, with staff trained to address the specific metabolic and aesthetic concerns prevalent in the region's demographics.
Joseph E. Sleiman· M.D.
Joseph E. Sleiman, M.D.
Founder and CEO
Owner and supervisor of Clinic 45, an independent medical spa and practice focusing on weight management, aesthetic services, and internal medicine consultations.
Topics Mentioned in Reviews
Weight Loss Program
Comprehensive medical weight loss program based on low-carbohydrate, high-fat approach with monthly follow-ups, body composition analysis, meal planning, and prescription medications when indicated
Semaglutide Injections
GLP-1 receptor agonist for weight management, weekly injection that slows digestion and reduces appetite
Tirzepatide Injections
Dual-agonist medication targeting both GLP-1 and GIP receptors for weight loss
B-12 Injections
Vitamin B-12 supplementation to boost metabolism and energy
Lipotropic Fat Burner Injections
Injections to strengthen metabolism and burn fat
Phentermine Pills
Appetite suppressant medication
Botox & Dermal Fillers
Injectable aesthetic treatments for facial rejuvenation
Microneedling
Skin rejuvenation treatment
Laser Hair Removal
Permanent hair reduction treatment
Vaginal Rejuvenation
Intimate wellness treatment
Skin Tightening
Non-invasive body contouring and skin tightening treatments
Internal Medicine Consultations
Comprehensive medical consultations and health assessments
IV Therapy
Intravenous nutrient therapy
Kybella
Injectable treatment for submental fat reduction
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