Dr. Diane Brzezinski

Dr. Diane Brzezinski operates an osteopathic medicine practice in Naples, Florida, where she integrates peptide therapy, bioidentical hormone replacement, and metabolic optimization protocols into individualized treatment plans. As a board-certified osteopathic internist holding FACOI designation from the American College of Osteopathic Internists, Dr. Brzezinski applies both conventional internal medicine training and osteopathic principles to address complex hormonal imbalances, age-related decline, and metabolic dysfunction. Her Naples clinic serves patients throughout Collier County and Southwest Florida seeking alternatives to standard pharmaceutical approaches for conditions including andropause, menopause, insulin resistance, and age-related muscle loss.

The clinic's peptide therapy protocols incorporate therapeutic peptides selected based on individual patient presentation and laboratory findings. Treatment options include growth hormone secretagogues for body composition optimization, thymosin peptides for immune modulation and tissue repair, and BPC-157 for gastrointestinal healing and musculoskeletal recovery. Dr. Brzezinski utilizes peptide combinations alongside bioidentical testosterone, estradiol, progesterone, and thyroid hormone replacement when indicated by comprehensive hormone panels. Weight loss programs integrate GLP-1 receptor agonists, metabolic support peptides, and nutritional protocols tailored to each patient's metabolic profile, insulin sensitivity, and body composition goals rather than following standardized protocols.

Dr. Brzezinski's osteopathic training informs her diagnostic approach, which emphasizes identifying root causes of hormonal disruption rather than symptom suppression alone. Initial consultations include detailed medical history review, physical examination incorporating osteopathic assessment techniques, and ordering of comprehensive laboratory panels measuring sex hormones, thyroid function, metabolic markers, inflammatory biomarkers, and nutrient status. She interprets lab results within functional ranges rather than relying solely on standard reference intervals, identifying subclinical imbalances that may contribute to fatigue, cognitive decline, decreased libido, or difficulty maintaining healthy body composition. Treatment plans evolve based on symptom response and follow-up laboratory monitoring, with peptide selection and dosing adjusted according to individual tolerance and therapeutic goals.

Patients at the Naples clinic typically begin with an extended initial consultation where Dr. Brzezinski reviews previous medical records, current symptoms, and treatment objectives. Following laboratory evaluation, she presents treatment options with explanation of expected timelines for clinical response, potential side effects, and monitoring requirements. Peptide therapy administration methods vary by compound and patient preference, including subcutaneous injection protocols that patients self-administer at home following in-office training. The clinic provides ongoing monitoring through scheduled follow-up visits, repeat laboratory testing at appropriate intervals, and dosage adjustments based on clinical response and biomarker changes. Patients receive specific protocols for peptide reconstitution, storage, and injection technique rather than generic instruction sheets.

Dr. Brzezinski's practice accepts patients seeking physician-supervised peptide therapy and hormone optimization who prefer an osteopathic perspective on age management and metabolic health. The Naples location provides access to patients throughout Southwest Florida including Fort Myers, Bonita Springs, and Marco Island. While the clinic maintains a 4.3-star rating across 78 Google reviews, prospective patients should schedule consultations to determine whether Dr. Brzezinski's treatment philosophy and available protocols align with their specific health objectives. The practice focuses on patients willing to participate actively in their treatment through lifestyle modification, regular monitoring, and adherence to prescribed protocols rather than those seeking passive interventions alone.