


Evolve 865 operates under the clinical direction of Jill Larson, APN-B, delivering hormone optimization, medical weight loss, and aesthetic services to patients throughout Lenoir City, Tennessee and the surrounding East Tennessee region. The practice focuses on evidence-based interventions for hormonal imbalances in both men and women, including testosterone replacement therapy for male hypogonadism and bioidentical hormone replacement for perimenopausal and postmenopausal women. Jill Larson holds board certification as an Advanced Practice Nurse and brings specialized training in functional medicine approaches to endocrine health, allowing the clinic to address root causes rather than symptoms alone.
The clinic's hormone therapy protocols begin with comprehensive laboratory panels that assess total and free testosterone, estradiol, progesterone, thyroid function, and metabolic markers. For men experiencing low testosterone, Evolve 865 offers multiple delivery methods including subcutaneous injections, topical formulations, and pellet therapy, with dosing individualized based on symptom response and follow-up labs. Women's hormone replacement programs utilize bioidentical estradiol and progesterone in forms such as transdermal creams, oral micronized capsules, and pellet implants, tailored to each patient's symptom profile and risk factors. The practice also integrates peptide therapies for patients seeking enhanced recovery, body composition improvement, or metabolic support, with protocols that may include sermorelin for growth hormone optimization and other research-backed peptides as clinically appropriate.
Medical weight loss programs at Evolve 865 combine pharmaceutical interventions with nutritional counseling and metabolic optimization. Jill Larson prescribes GLP-1 receptor agonists such as semaglutide when indicated, alongside appetite suppressants, lipotropic injections, and individualized macronutrient plans. Each weight loss patient receives baseline body composition analysis and metabolic rate testing to establish personalized caloric targets and exercise recommendations. The clinic's approach addresses underlying hormonal contributors to weight gain, including thyroid dysfunction, insulin resistance, and sex hormone imbalances, ensuring that weight loss efforts are supported by optimized endocrine function rather than calorie restriction alone.
Patients at Evolve 865 typically begin with an initial consultation that includes a detailed health history, symptom assessment, and discussion of treatment goals, followed by laboratory testing ordered through LabCorp or Quest Diagnostics. Results are reviewed in a follow-up visit where Jill Larson explains findings in detail and presents treatment options with expected timelines and monitoring requirements. Hormone therapy patients return for follow-up labs at 6-8 weeks after initiation and then quarterly once stable, with dosing adjustments made based on both objective lab values and subjective symptom improvement. The clinic also offers aesthetic treatments including neurotoxin injections, dermal fillers, and medical-grade facials, allowing patients to address both internal wellness and external appearance concerns in a single practice setting. IV nutrient therapy is available for patients seeking hydration support, immune enhancement, or recovery from illness or athletic exertion.
Located in Lenoir City, Tennessee, Evolve 865 serves patients from Knoxville, Oak Ridge, Maryville, and throughout Loudon County, with office hours structured to accommodate working professionals. The practice maintains a patient-centered model where Jill Larson personally oversees all treatment plans and conducts follow-up consultations, ensuring continuity of care and clinical accountability. New patients can expect thorough education about hormone physiology, realistic timelines for symptom improvement, and transparent discussion of costs, as many services are not covered by insurance. The clinic's integration of hormone therapy, weight management, and aesthetic medicine allows patients to pursue comprehensive wellness goals under a single provider with specialized training in age management and functional endocrinology.
Jill Larson· APN-B
Jill Larson, APN-B
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