Gretchen Reis, MD

Gretchen Reis, MD operates Integrity Wellness MD in Charlotte, NC, delivering anti-aging and functional medicine services with a focus on hormone optimization, metabolic health, and evidence-based peptide therapies. Dr. Reis holds a Fellowship in Anti-Aging, Functional and Regenerative Medicine from the American Academy of Anti-Aging Medicine, bringing advanced training in hormone modulation and age-related metabolic dysfunction to her practice. Her clinical model emphasizes root-cause analysis and personalized treatment protocols designed to address fatigue, weight gain, hormonal imbalance, and age-related decline in both men and women.

The clinic offers Semaglutide and Tirzepatide as part of its medical weight loss and metabolic optimization programs. Semaglutide, a GLP-1 receptor agonist, is prescribed to patients seeking appetite regulation, improved glycemic control, and sustainable fat loss. Tirzepatide, a dual GIP/GLP-1 receptor agonist, is utilized for patients requiring more robust metabolic support, particularly those with insulin resistance or elevated hemoglobin A1c. Both peptides are integrated into comprehensive treatment plans that include nutritional counseling, lab monitoring, and ongoing dosage adjustments based on patient response. Dr. Reis tailors peptide therapy to individual metabolic profiles, ensuring safe and effective outcomes for weight management and cardiometabolic health.

Bioidentical hormone replacement therapy is a cornerstone of the practice, particularly for women navigating perimenopause and menopause. Dr. Reis evaluates hormone panels including estradiol, progesterone, testosterone, thyroid function, and cortisol to design replacement protocols that alleviate hot flashes, mood disturbances, sleep disruption, and loss of libido. Hormone therapy is delivered through creams, pellets, or oral formulations depending on patient preference and clinical indication. Men experiencing andropause or low testosterone are also treated with bioidentical hormone optimization to restore energy, muscle mass, and cognitive function. Each patient undergoes baseline lab work and follow-up testing to monitor hormone levels and adjust therapy as needed.

Patients at Integrity Wellness MD begin with a comprehensive consultation that includes a detailed health history, symptom review, and discussion of wellness goals. Dr. Reis takes time to explain the physiological mechanisms behind symptoms such as fatigue, weight gain, brain fog, and hormonal imbalance, empowering patients to understand their treatment options. Lab panels are ordered to assess metabolic markers, hormone levels, nutrient deficiencies, and inflammatory markers. Follow-up visits are scheduled to review results, initiate therapy, and track progress. The clinic's approach is collaborative, with Dr. Reis addressing patient questions and adjusting protocols based on real-time feedback and lab data.

Located in Charlotte, Integrity Wellness MD serves patients throughout Mecklenburg County and the greater Charlotte metropolitan area. The practice is designed for individuals seeking an alternative to conventional primary care, particularly those frustrated by symptom management without investigation of underlying causes. Dr. Reis combines her fellowship training with a patient-centered philosophy, offering longer appointment times and direct access for questions between visits. The clinic's high patient satisfaction reflects its commitment to thorough evaluation, transparent communication, and individualized care plans that prioritize long-term wellness over short-term symptom suppression.