Integrity Wellness MD

Integrity Wellness MD operates as a comprehensive functional and regenerative medicine practice in Charlotte, NC, led by Dr. Gretchen Reis, a board-certified physician who completed a Fellowship in Anti-Aging, Functional and Regenerative Medicine through the American Academy of Anti-Aging Medicine. The clinic addresses hormone imbalances, metabolic dysfunction, gut health disorders, and age-related decline through evidence-based protocols that combine advanced diagnostics with targeted interventions. Dr. Reis structures treatment plans around individual lab findings and symptom patterns rather than standardized protocols, with particular emphasis on identifying root causes of fatigue, weight resistance, cognitive changes, and sexual health concerns that conventional medicine often attributes solely to aging.

The practice offers both semaglutide and tirzepatide for medical weight loss, integrating these GLP-1 receptor agonists into broader metabolic optimization programs that address insulin resistance, inflammatory markers, and hormonal contributors to weight gain. Patients in Charlotte seeking peptide therapy for weight management receive comprehensive metabolic panels before starting treatment, with ongoing monitoring of thyroid function, cortisol patterns, and sex hormone levels that frequently influence treatment response. Bioidentical hormone replacement therapy represents a core service, with Dr. Reis prescribing individualized hormone protocols for both perimenopausal and menopausal women as well as men experiencing andropause, using pellet therapy, topical preparations, or injectable options based on patient preference and physiological response. The clinic's approach to hormone optimization extends beyond symptom relief to include bone density preservation, cardiovascular risk reduction, and cognitive function support.

Dr. Reis conducts in-person consultations at the Charlotte location, dedicating extended appointment times to review patient histories, current symptoms, lifestyle factors, and previous treatment attempts. Her fellowship training informs a clinical approach that examines interactions between hormonal systems, gut microbiome health, mitochondrial function, and inflammatory pathways rather than treating isolated symptoms. Patients with complex presentations involving multiple body systems—such as those experiencing concurrent digestive issues, hormonal imbalances, and metabolic concerns—receive coordinated treatment plans that address interconnected physiological processes. The practice maintains a 4.9-star rating across 108 Google reviews, with patients frequently noting Dr. Reis's thoroughness in explaining test results, her willingness to answer detailed questions about treatment mechanisms, and her collaborative approach to adjusting protocols based on patient feedback and follow-up lab work.

New patients at Integrity Wellness MD undergo comprehensive initial evaluations that typically include detailed hormone panels, metabolic markers, nutrient status testing, and assessment of inflammatory biomarkers, with Dr. Reis using these baseline measurements to design treatment protocols and track objective progress over time. The clinic's sexual wellness programs address both male and female concerns through hormone optimization, peptide therapy when indicated, and treatments targeting vascular health and tissue regeneration. For gut health issues, the practice employs functional stool testing, food sensitivity panels, and targeted protocols to restore microbiome balance and intestinal barrier integrity, recognizing that digestive dysfunction frequently underlies hormone imbalances, immune dysregulation, and metabolic disorders. Follow-up visits allow for treatment refinement based on symptom resolution, lab value changes, and patient-reported quality of life improvements.

Integrity Wellness MD serves Charlotte and surrounding North Carolina communities with a practice model that prioritizes patient education alongside treatment implementation, with Dr. Reis explaining the physiological rationale behind recommended interventions and how specific treatments address identified imbalances. The clinic's preventative medicine focus includes optimization protocols for patients not yet experiencing significant symptoms but seeking to maintain cognitive function, metabolic health, and physical vitality as they age. Patients pursuing weight loss through semaglutide or tirzepatide receive nutritional guidance, metabolic support, and monitoring for the hormonal and metabolic shifts that influence long-term weight maintenance beyond the medication phase. The practice's regenerative medicine approach extends to addressing early signs of aging, declining energy production at the cellular level, and the cumulative effects of chronic stress on multiple body systems.