Novo Aesthetics

Novo Aesthetics operates as a dual-focus clinic in Sioux Falls, South Dakota, combining prescription weight management programs with comprehensive medical spa treatments. The practice has built a telehealth infrastructure serving patients across South Dakota, Minnesota, and Iowa, allowing residents in these three states to access GLP-1 receptor agonist therapy without requiring in-person visits for initial consultations or ongoing medication management. This regional telehealth model addresses the growing demand for medically supervised weight loss in the upper Midwest, where access to specialized metabolic medicine providers remains limited in rural and suburban communities.

The clinic's weight management protocol centers on two FDA-approved GLP-1 medications: semaglutide and tirzepatide. Semaglutide functions as a glucagon-like peptide-1 receptor agonist that regulates appetite and glucose metabolism through hypothalamic pathways, while tirzepatide operates as a dual GIP/GLP-1 receptor agonist, engaging both glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptors for enhanced metabolic effect. Novo Aesthetics structures these programs with individualized dosing schedules, regular provider communication via text and telehealth check-ins, and ongoing adjustments based on patient response and tolerance. The practice provides detailed medication education during the onboarding process, covering injection technique, expected timelines for appetite suppression, common side effects like nausea or gastrointestinal changes, and strategies for optimizing nutrition during active weight loss phases. Patients receive their medications through partner pharmacies with direct shipping to their homes in Minnesota, Iowa, or South Dakota.

Beyond peptide-based weight management, Novo Aesthetics maintains a physical location in Sioux Falls offering regenerative aesthetic procedures, most notably platelet-rich plasma (PRP) therapy for skin rejuvenation and hair restoration. PRP treatments involve drawing a patient's own blood, processing it to concentrate growth factors and cytokines, then reinjecting this autologous preparation into targeted areas to stimulate collagen production, improve skin texture, and promote tissue repair. The clinic's med spa services complement the metabolic health focus by addressing body composition changes, skin laxity, and aesthetic concerns that often accompany significant weight loss. This integrated approach allows patients to coordinate their weight management and aesthetic goals under one practice umbrella, with providers who understand how rapid fat loss affects skin elasticity and facial volume.

The patient experience at Novo Aesthetics emphasizes accessibility and responsive communication, reflected in the clinic's 5.0-star rating across 216 Google reviews. Patients consistently reference the ease of asking questions, the clarity of treatment plans, and the availability of providers through text-based communication channels between scheduled appointments. For telehealth weight loss patients in Minnesota, Iowa, and South Dakota, the intake process begins with an online health assessment and virtual consultation to review medical history, current medications, weight loss goals, and candidacy for GLP-1 therapy. Providers evaluate contraindications such as personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2, or severe gastrointestinal disease before prescribing semaglutide or tirzepatide. Follow-up appointments occur monthly via telehealth to monitor progress, adjust dosing, and address any emerging concerns.

Novo Aesthetics differentiates itself in the Sioux Falls market through its hybrid model—offering the convenience of remote weight management for patients across three states while maintaining hands-on aesthetic services for those seeking in-person treatments like PRP. The clinic's focus on education and communication, evidenced by patient feedback regarding informative consultations and clear medication guidance, positions it as a resource for individuals who want structured support rather than prescription-only services. For residents of South Dakota, Minnesota, and Iowa seeking medically supervised weight loss with semaglutide or tirzepatide, or for Sioux Falls-area patients interested in combining metabolic therapy with regenerative aesthetics, Novo Aesthetics provides a regionally accessible option with documented patient satisfaction and a defined scope of peptide and aesthetic offerings.