


TrueBio Innovative Health + Wellness, PLLC operates as a hormone optimization and functional medicine clinic in Winston-Salem, North Carolina, focusing on bio-identical hormone replacement therapy (BHRT), metabolic health, and gastrointestinal wellness. The practice addresses hormonal transitions including perimenopause, menopause, and age-related testosterone decline through evidence-based protocols that integrate hormone pellet therapy, nutritional interventions, and targeted supplementation. As an EvexiPEL Certified Provider, TrueBio utilizes subcutaneous hormone pellet implants that deliver consistent estradiol and testosterone levels over three to six months, eliminating the daily dosing variability associated with creams, patches, or oral medications. This certification requires specialized training in pellet insertion technique, dosing algorithms based on body composition and symptom presentation, and ongoing competency verification, distinguishing the clinic's technical proficiency in this delivery method.
The clinic's treatment protocols extend beyond hormone replacement to address the interconnected systems that influence metabolic function and overall vitality. For weight management, TrueBio implements medically supervised programs that may incorporate GLP-1 receptor agonists, appetite regulation support, and metabolic testing to identify underlying factors such as insulin resistance, thyroid dysfunction, or cortisol dysregulation. Gut health services target digestive complaints, inflammatory conditions, and microbiome imbalances through comprehensive stool analysis, elimination protocols, and therapeutic nutrition plans designed to restore intestinal barrier function and optimize nutrient absorption. The practice recognizes that hormonal balance, metabolic efficiency, and gastrointestinal health operate as interdependent variables, structuring treatment plans that address multiple systems simultaneously rather than isolating single symptoms.
TrueBio's providers conduct in-person consultations in Winston-Salem, performing initial assessments that include detailed symptom inventories, medical history review, and laboratory evaluation of hormone panels, metabolic markers, and nutrient status. The clinic orders comprehensive testing that may include estradiol, progesterone, total and free testosterone, thyroid function (TSH, Free T3, Free T4), vitamin D, B12, iron studies, and inflammatory markers to establish baseline values and guide treatment customization. Follow-up protocols involve scheduled lab monitoring to track hormone levels post-pellet insertion, assess treatment response, and adjust dosing for subsequent implants. Providers explain the pharmacokinetics of pellet therapy, including the expected timeline for symptom improvement, the gradual release curve of hormones from the pellet matrix, and the importance of maintaining consistent follow-up to prevent under- or over-dosing.
Patients at TrueBio receive individualized treatment plans that account for their specific hormone deficiency patterns, symptom severity, metabolic health status, and personal health goals. The clinic's approach involves educating patients on how declining estrogen affects bone density, cardiovascular risk, and cognitive function in women, while testosterone deficiency in both men and women contributes to reduced muscle mass, increased body fat, diminished libido, and decreased energy. Treatment plans may combine hormone pellet therapy with nutritional counseling, targeted supplementation for identified deficiencies, and lifestyle modification strategies addressing sleep quality, stress management, and physical activity. The practice structures care to provide ongoing support rather than one-time interventions, with regular check-ins to assess treatment efficacy and make protocol adjustments based on patient response.
TrueBio Innovative Health + Wellness serves the Winston-Salem community and surrounding Forsyth County area through its in-person consultation model, requiring patients to visit the clinic for initial evaluations, pellet insertions, and follow-up assessments. This hands-on approach allows providers to perform physical examinations, conduct in-office procedures, and build therapeutic relationships that facilitate detailed health discussions and personalized care adjustments. The clinic's focus on hormone optimization positions it as a resource for individuals experiencing the physiological changes of aging, those seeking alternatives to conventional hormone replacement methods, and patients who have not achieved satisfactory results with other treatment modalities. By maintaining EvexiPEL certification and integrating hormone therapy with metabolic and gastrointestinal support, TrueBio offers a comprehensive approach to age management and functional wellness in the Winston-Salem medical community.
Amanda McNeil, DNP, FNP-BC
Owner, operator of True Bio Innovative Health + Wellness, PLLC
Amanda McNeil, DNP, FNP-BC is a nationally board-certified Family Nurse Practitioner. With an earned Bachelor of Science in Nursing from University of North Carolina at Charlotte, Master of Science in Nursing, Family and Adult Nurse Practitioner from University of San Diego, and Doctor of Nursing Practice from Duke University, she is well-equipped to provide exceptional healthcare. Serving as the foundation of her work, Dr. McNeil’s passion is to make a positive difference in the lives of her patients and community by providing evidenced-based, high quality health and wellness services. She has further expanded her education to include integrative medical wellness; achieving the prestigious certification as an EvexiPEL ® provider to provide the most current, evidence-based hormone optimization therapies. As a US Navy Nurse Corp Veteran, Dr. McNeil brings a rich background with 32 years in health care. Her experience includes primary care, health and wellness, bio-identical hormone replacement and optimization therapy including hormone pellet placement, weight management, thyroid management, public health, urgent care, and emergency medicine. She believes in treating the whole person by discovering the root cause of problems rather than using a band-aid approach to treating symptoms.
Amber Caldwell, FNP-BC
Amber is a native to the triad area. She graduated with an associates degree in nursing in 2006 and completed her bachelor’s degree in 2009. She worked as a nurse in ER and ICU. She later completed her Master of Science in Nursing at the University of North Carolina at Chapel Hill and holds a certification in Family Primary Care from the American Association of Nurse Practitioners. She worked in urgent care settings before transitioning to integrative/preventative medicine with a focus on hormone replacement therapy and weight loss in 2017.
Kathryn Skinner, Nutritionist-Functional Medicine Health Coach-Clinical Manager
Kathryn graduated from UNCG with a bachelor's in nutrition and wellness. After coaching individuals and desiring to learn more she earned her certification as a Functional Medicine Health Coach. Combined with her 5+ years of teaching yoga she counsels with a well-rounded approach: informing, guiding and challenging in order to help individuals grow toward their better selves.
Jocelyn Martinez, Certified Nursing Assistant-Medical Assistant
Jocelyn is a dedicated CNA and Medical Assistant with 16 years of experience in healthcare. She is passionate about providing high-quality care and helping others on their wellness journey.
Ashlyn Hall, Licensed Esthetician
With a deep passion for skincare and beauty, Ashlyn is dedicated to helping clients feel confident and comfortable in their own skin. She is trained in facials, chemical peels, lash and brow treatments, and a variety of advanced skincare techniques. A firm believer in continuing education, Ashlyn stays up to date with the latest innovations in skincare to ensure the best possible results for her clients. Ashlyn creates personalized treatment plans tailored to each client’s unique skin concerns and goals. She is known for her attention to detail, thorough skin evaluations, and commitment to delivering visible, lasting improvements.
Jon Kite, Business Operations Manager
Co-Owner of Osteostrong
Jon is a Forsyth County native with 25+ years experience owning and operating multiple SubWay Franchises throughout Winston-Salem. Jon is passionate about working with others and offering the community of Winston-Salem and surrounding areas an alternative solution to improving bone strength beyond traditional weight resistance training and pharmaceutical options.
Topics Mentioned in Reviews
Bio Identical Hormone Therapy
We offer a variety of bio-identical hormone therapies for both men and women, including our specialty treatment known as pellet therapy. This approach provides a reliable and effective way to balance hormones naturally.
Perimenopause/Menopause
Specialized services for women experiencing perimenopause and menopause.
Male Hormone Optimization
Services focused on optimizing male hormone levels.
Bone Health, Osteopenia & Osteoporosis
Services aimed at improving bone health and managing conditions like osteopenia and osteoporosis.
Pelvic Health & Vaginal Rejuvenation
Services focused on pelvic health and rejuvenation.
Nutrition and Lifestyle
Guidance on nutrition and lifestyle changes for better health.
Health and Wellness
Comprehensive health and wellness services.
Aesthetics
Aesthetic services to enhance beauty and wellness.
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