Charleston Hormone Services (CHS)

Charleston Hormone Services operates from Mt Pleasant, South Carolina, delivering hormone replacement therapy, peptide therapy, weight management, and thyroid optimization under the clinical direction of Stephanie Donovan, MSN, NP-C. The practice focuses on addressing hormonal imbalances in women navigating perimenopause, menopause, and metabolic dysfunction, combining bioidentical hormone replacement with targeted peptide protocols. CHS serves patients throughout the Charleston metro area with in-person consultations designed to establish individualized treatment plans based on comprehensive lab work and symptom assessment.

The clinic incorporates GHK-Cu peptide therapy into treatment protocols for patients seeking support with tissue repair, skin health, and anti-inflammatory benefits alongside hormone optimization. GHK-Cu, a naturally occurring copper peptide, is utilized for its regenerative properties and is often integrated into programs addressing aesthetic concerns and recovery from hormonal decline. Hormone replacement therapy at CHS includes bioidentical estrogen, progesterone, and testosterone formulations tailored to each patient's lab results and clinical presentation. Thyroid management addresses subclinical hypothyroidism, Hashimoto's thyroiditis, and thyroid hormone conversion issues through medication adjustments, nutrient support, and lifestyle modification. Weight management programs combine metabolic hormone balancing with nutritional guidance and accountability structures to address insulin resistance and stubborn weight patterns common in midlife women.

Stephanie Donovan brings her Master of Science in Nursing and board certification as a nurse practitioner to every patient interaction, conducting thorough intake assessments that review medical history, current symptoms, and treatment goals. Her clinical approach emphasizes education, ensuring patients understand the physiological mechanisms behind their symptoms and the rationale for each intervention. Donovan evaluates hormone panels including estradiol, progesterone, testosterone, DHEA, cortisol, thyroid function markers, and metabolic indicators to create evidence-based treatment plans. Follow-up visits include symptom tracking, lab monitoring, and protocol adjustments to optimize outcomes while minimizing side effects. The practice maintains a patient-centered model where treatment decisions are made collaboratively, with Donovan providing clinical expertise while respecting patient preferences and lifestyle considerations.

Patients at Charleston Hormone Services can expect an initial consultation lasting 60 to 90 minutes, during which Donovan conducts a detailed health history review and orders baseline laboratory testing. Once labs are completed, a follow-up visit reviews results and establishes the treatment protocol, including hormone dosing, peptide administration instructions, and supplement recommendations when indicated. The office provides clear guidance on medication administration, whether through topical creams, sublingual troches, or subcutaneous injections for peptides. Patients receive written protocols and have access to the clinical team for questions during the adjustment phase. Follow-up appointments are scheduled at intervals appropriate to the treatment type—typically 6 to 12 weeks initially, then extending to quarterly visits once stable. The practice also addresses aesthetic concerns related to hormonal aging, offering guidance on skincare protocols and supplements that support collagen production and skin elasticity.

Charleston Hormone Services operates exclusively through in-person visits at the Mt Pleasant location, allowing for hands-on assessment and direct patient-provider interaction. This model supports continuity of care and enables Donovan to monitor physical changes, review injection techniques, and adjust treatments based on real-time clinical observation. The practice has earned a 5.0-star rating across 215 Google reviews, with patients frequently noting the thoroughness of consultations, the clarity of information provided, and the effectiveness of HRT protocols in resolving symptoms like hot flashes, brain fog, fatigue, and weight gain. The office environment is designed to facilitate open conversation about sensitive health topics, and the administrative team supports patients with insurance questions, prescription coordination, and appointment scheduling. For women in the Charleston area seeking hormone optimization grounded in clinical expertise and individualized care, CHS provides a structured, evidence-informed approach to managing the physiological transitions of perimenopause and menopause.