


Dr. Robert Rubin operates a functional medicine practice in Naples, Florida, combining his board certifications in Internal Medicine and Geriatrics Medicine with advanced training as a Fellow of the American Academy of Anti-Aging Medicine. His clinic addresses age-related decline, metabolic dysfunction, and hormonal imbalances through peptide therapy, bioidentical hormone replacement, and evidence-based wellness protocols. Recognized by Castle Connolly Medical as a Top Doctor in South Florida for four consecutive years, Dr. Rubin applies decades of clinical experience to personalized treatment plans that target root causes rather than symptoms alone.
Dr. Robert Rubin - Naples's peptide therapy menu includes Copper Peptides, Semaglutide, and Tirzepatide, with treatment protocols customized based on individual health goals and lab work. Additional peptide options may be available based on medical necessity and FDA guidelines.
Dr. Rubin's approach to hormone optimization integrates bioidentical hormone replacement therapy with peptide protocols, particularly for patients experiencing andropause, menopause, or age-related hormonal shifts. His background in geriatric medicine informs treatment strategies that account for comorbidities, polypharmacy risks, and age-specific physiological changes. For men's health, the clinic addresses erectile dysfunction through a combination of vascular assessment, hormone correction, and peptide therapy, moving beyond single-intervention models. Women's health services include perimenopausal and menopausal management with bioidentical hormones, metabolic support, and peptides targeting bone density, skin elasticity, and cognitive function. Platelet-rich plasma therapy is incorporated for joint health, hair restoration, and aesthetic applications, often synergizing with peptide treatments like BPC-157 and GHK-Cu.
Patients at the Naples clinic undergo comprehensive initial evaluations that include detailed health histories, symptom assessments, and targeted laboratory panels measuring hormone levels, metabolic markers, and inflammatory indicators. Dr. Rubin reviews results in one-on-one consultations, explaining the rationale behind each recommended intervention and setting realistic expectations for timelines and outcomes. The practice operates on a hybrid model, offering both in-person visits at the Naples location and telehealth consultations for established patients or those requiring follow-up care. This flexibility accommodates Southwest Florida residents as well as patients from surrounding counties who prefer remote access for routine monitoring.
Working with a partnered compounding pharmacy, the clinic ensures peptide quality, proper reconstitution protocols, and patient education on self-administration techniques. Staff provide injection training during initial visits, and patients receive detailed written instructions along with video resources. Follow-up schedules are individualized based on treatment type, with weight loss patients typically seen every four to six weeks and hormone optimization patients monitored quarterly. Dr. Rubin's practice emphasizes data-driven adjustments, using symptom tracking and repeat labs to refine dosing and combination therapies. The clinic's focus remains on sustainable health improvements rather than short-term interventions, aligning treatment intensity with each patient's long-term wellness goals and medical complexity.
Robert Rubin· MD
Robert Rubin, MD, Advanced Fellow American Academy of Anti-Aging Medicine, AMA Board Certified in Internal Medicine and Geriatrics Medicine
Physician
Dr. Rubin is a widely respected functional medicine practitioner in Florida with offices in Naples and Tampa. He spent the first 25 years of his medical career working in internal and geriatric medicine, successfully becoming one of Florida's Sun Coast top-rated physicians. For four years, Castle Connolly Medical, Ltd. recognized him as one of the 'Top Doctors' in South Florida. After further specialized training, he shifted his practice to a functional medicine approach. Over the last 15 years, Dr. Rubin has honed his focus creating a practice rooted in evidence-based healthcare that addresses the root causes of symptoms.
Bioidentical Hormone Replacement Therapy (BHRT)
Hormone replacement therapy using bioidentical hormones to normalize low or imbalanced hormones in men and women
Pellet Therapy
Hormone pellets implanted under the skin that dissolve over time, gradually releasing hormones
BHRT Creams
Bioidentical hormone replacement therapy administered via topical creams
BHRT Shots
Bioidentical hormone replacement therapy administered via injections
Platelet-Rich Plasma (PRP) Therapy
Injections of concentrated platelets from your own blood to accelerate healing and tissue regeneration
P-Shot
PRP therapy for men to treat erectile dysfunction and improve sexual function
O-Shot
PRP therapy for women to improve sexual function and treat urinary incontinence
PRP for Hair Loss
Platelet-rich plasma therapy to treat hair loss
PRP for Pain Management
PRP therapy for musculoskeletal disorders, injured muscles, ligaments, and tendons
Shockwave Therapy
Low-intensity extracorporeal shock wave therapy for erectile dysfunction treatment
Peptide Therapy
Therapy using peptides like BPC-157, PT-141, CJC-1295, Ipamorelin, Sermorelin, and GHK-CU for various health benefits
PT-141 Peptide Therapy
Peptide therapy to improve sexual response and increase libido for men and women
Copper Peptide GHK-CU Therapy
Peptide therapy for skin rejuvenation with regenerative and collagen-stimulating properties
Medical Weight Loss
Personalized weight loss program including medication-assisted options
Semaglutide Injections
GLP-1 medication for weight loss that regulates appetite and insulin
+3 more services — contact clinic for full list
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