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MyPeptideMatch
Telehealth Comparison · 2026

AgelessRx vs Defy Medical: Which Is Better?

For most patients, Defy Medical edges out AgelessRx on our editorial score — veteran trt & hormone optimization clinic. That said, AgelessRx can be the better fit depending on price, treatment menu, and what your consultation reveals — see the side-by-side below.

AgelessRx logo
AgelessRx

Best longevity-focused telehealth (NAD+, rapamycin)

4.4/5 (2,258)7.8/10 editorialFrom $85/mo
Anti-Aging & Longevity
Our pick
Defy Medical logo
Defy Medical

Veteran TRT & hormone optimization clinic

4.8/5 (3,784)8.1/10 editorial
Weight LossHormone OptimizationSexual Wellness

Side-by-side comparison

FeatureAgelessRxDefy Medical
Starting price$85/moNot disclosed
Customer rating4.4/5 (2,258)4.8/5 (3,784)
Editorial score7.8/108.1/10
Medication typeCompounded (503A/503B pharmacies)Compounded (503A/503B pharmacies)
ConsultationAsync messagingLive video visit
Best forAnti-Aging & LongevityWeight Loss, Hormone Optimization, Sexual Wellness
Treatments listed22

Treatments offered

Both offer (0)

None.

Only at AgelessRx (2)

Only at Defy Medical (2)

AgelessRx — pros & cons

Pros

  • +Longevity-medicine specialist
  • +Topical and injectable formats
  • +Free online medical evaluation

Cons

  • Limited peptide catalog vs specialists
  • Higher price for some compounded items

Defy Medical — pros & cons

Pros

  • +Established hormone & TRT clinic with a deep menu
  • +Bioidentical HRT, peptides, and sexual wellness
  • +Physician-supervised phone + telemedicine

Cons

  • Pricing not transparent online
  • Concierge model can be pricey

Frequently asked questions

AgelessRx vs Defy Medical: which is better?

For most patients, Defy Medical edges out AgelessRx on our editorial score — veteran trt & hormone optimization clinic. That said, AgelessRx can be the better fit depending on price, treatment menu, and what your consultation reveals — see the side-by-side below.

Do AgelessRx and Defy Medical offer the same treatments?

AgelessRx and Defy Medical focus on different treatment menus — see the treatments section above to compare what each prescribes.

Are AgelessRx and Defy Medical legit?

Both are US telehealth providers that connect patients with licensed clinicians and ship prescriptions from partner pharmacies. AgelessRx holds a 4.4/5 rating from 2,258 verified Trustpilot reviews. Defy Medical holds a 4.8/5 rating from 3,784 verified Trustpilot reviews. Treatment eligibility is determined during a clinical consultation.

Affiliate disclosure: Some links on this page are affiliate links — if you start treatment through one, we may earn a commission at no additional cost to you. Editorial rankings and opinions are independent of commercial relationships. See our affiliate disclosure.