Triptorelin is a synthetic decapeptide analog of gonadotropin-releasing hormone (GnRH; pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH₂). It binds to the GnRH receptor, initiating Gq/PLC and IP₃–Ca²⁺ signaling cascades that regulate luteinizing and follicle-stimulating hormone release in experimental systems. Triptorelin is used in receptor biology and endocrine regulation research to study hypothalamic–pituitary–gonadal axis modulation.
