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Reviewed by MyPeptideMatch Editorial TeamLast reviewed February 2026Updated February 2026

BPC-157 Dosing Protocol: 10 mg Vial — Extended Supply Dosing Guide

BPC-157 10 mg vial guide for multi-week injury repair cycles at 500 µg/day, with supplies checklist and oral dosing option.

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Quickstart highlights

BPC-157 at 500 µg/day in rat models demonstrates complete Achilles tendon transection healing within 3 weeks versus 8+ weeks for controls (Šebečić et al., 1999).

  • Concentration: 2 mg/mL (10 mg vial + 5 mL bacteriostatic water).
  • At 2 mg/mL: 250 µg = 12.5 units, 500 µg = 25 units per injection.
  • One 10 mg vial provides 20 daily doses at 500 µg — approximately 3 weeks of treatment.
  • Inject subcutaneously near injury site for musculoskeletal repair; abdominally for gut/systemic use.
  • Refrigerate; use within 28 days.

Dosing table

For educational reference only. Your prescribing provider may adjust doses based on your clinical profile and response.

WeekDose (µg)UnitsFrequencyNotes
1-425012.5Once daily250 µg — 12.5 units; 10 mg vial provides 40 doses at this level (40 days)
5-1250025Once daily500 µg — 25 units; 20 doses per vial (20 days at standard dose)

Reconstitution steps

  1. Draw 5 mL bacteriostatic water (two 2.5 mL draws); inject slowly down the vial wall.
  2. Swirl gently until fully dissolved; do not shake.
  3. Final concentration: 2 mg/mL. Label with date; refrigerate at 2–8 °C. Use within 28 days.

Supplies needed

8-week plan

  • 1 vial
  • 56 syringes
  • 5 mL bac water
  • 56 alcohol swabs

12-week plan

  • 2 vials
  • 84 syringes
  • 10 mL bac water
  • 84 alcohol swabs
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Protocol overview & cycle notes

Provide an extended 20-day BPC-157 supply from the 10 mg vial at the standard 500 µg/day dose, suitable for acute injury protocols or chronic repair cycles requiring multi-week continuous treatment.

Cycle length: 12 weeks on.

Off-cycle: 4 weeks off after each 12-week cycle.

Storage & handling

Lyophilized: store below 25 °C. Reconstituted at 2 mg/mL: refrigerate 2–8 °C; use within 28 days. One 10 mg vial provides 20 days at 500 µg/day.

Injection & tracking tips

  • The 10 mg vial covers 20 daily doses at 500 µg — reducing reconstitution frequency versus the 5 mg vial.
  • For bilateral injuries (both shoulders, both knees), split the 500 µg dose (250 µg per side) to treat both simultaneously.
  • Mark each daily dose on a calendar to track vial usage and ensure the 28-day use window is respected.

Tracking

Logging helps you and your provider spot patterns and adjust dose or timing.

  • Rate pain severity (0–10 VAS) daily for the target injury.
  • Track activity/exercise capacity weekly as a functional recovery metric.
  • For gut protocols: log daily bowel transit, bloating (0–10), and acid reflux frequency.
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How this works & references

BPC-157 at 500 µg/day in rat models demonstrates complete Achilles tendon transection healing within 3 weeks versus 8+ weeks for controls (Šebečić et al., 1999). The 10 mg vial enables 20 consecutive daily injections without reconstitution, reducing sterility risk. Sikiric et al. (2011) documented cytoprotective, angiogenic, and anti-inflammatory effects across multiple organ systems in comprehensive rat model studies.

Sources

  • Source: Šebečić B et al. — BPC-157 in bone and tendon healing. J Orthop Res. 1999
  • Source: Sikiric P et al. — BPC-157: cytoprotective across multiple systems. Curr Pharm Des. 2011

Frequently asked questions

Is twice-daily BPC-157 dosing more effective than once daily?
Animal model evidence (Sikiric et al.) used both once-daily and twice-daily protocols; twice-daily dosing (250 µg AM and PM) may accelerate healing for acute injuries. Many practitioners use twice-daily for the first 4 weeks of an acute injury, then drop to once-daily for maintenance. At 500 µg twice daily, a 10 mg vial lasts 10 days.
Can I use BPC-157 for gut healing alongside other treatments?
Yes — BPC-157 is compatible with PPIs, H2 blockers, and most GI medications. It may reduce reliance on PPIs for acid-related conditions and has shown intestinal fistula-healing properties in rat models. Discuss with your gastroenterologist before combining with prescription GI therapies.
Does BPC-157 work for neurological injuries?
Rat models suggest BPC-157 promotes motor neuron recovery after sciatic nerve crush injury (Sikiric et al., 2001). The mechanism involves NO pathway activation and VEGF-driven repair at the axonal level. Anecdotal human use for nerve injury recovery exists but no controlled human data is published.
How do I dose BPC-157 for leaky gut or IBD?
For gut healing, oral administration at 250–500 µg daily on an empty stomach (30 minutes before breakfast) is preferred. The peptide survives gastric acid and reaches the intestinal mucosa, where it activates mucosal repair pathways. Some practitioners also use subcutaneous abdomen injection as an alternative.
Is BPC-157 safe for long-term use?
No long-term human safety data exists. Animal toxicology studies (up to 24 months in rats) have not identified significant adverse effects. The recommended approach is 12-week cycles with 4-week off periods. Monitor liver enzymes and kidney function annually with long-term use.

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This content is for informational purposes only and does not constitute medical advice. Consult a licensed healthcare provider before starting any peptide therapy. Dosing and protocols may vary by formulation and prescriber.

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