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Reviewed by MyPeptideMatch Editorial TeamLast reviewed February 2026Updated February 2026

Prostamax Dosing Protocol: 20 mg Vial — Prostate Bioregulator Guide

Prostamax (Lys-Asp-Glu-Leu tetrapeptide) Russian prostate bioregulator dosing guide — prostatic epithelial gene normalization for BPH, prostate aging, and urinary symptom support.

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Quickstart highlights

Prostamax (Lys-Asp-Glu-Leu) is a tetrapeptide bioregulator from Khavinson's group targeting prostatic epithelial tissue.

  • Concentration: 2 mg/mL (20 mg + 10 mL bac water).
  • At 2 mg/mL: 200 µg = 10 units daily x 10 days.
  • Targets prostatic epithelial gene expression: androgen receptor, IL-8, TNF-alpha normalization.
  • Monitor PSA before each course — not a treatment for confirmed prostate cancer.
  • One 20 mg vial = 100 doses; suitable for 10 complete 10-day courses.

Dosing table

For educational reference only. Your prescribing provider may adjust doses based on your clinical profile and response.

WeekDose (µg)UnitsFrequencyNotes
1-2 (10-day course)20010Once daily200 µg — 10 units; 10-day course; 20 mg vial = 100 doses
Maintenance20010Every other day200 µg EOD — prostate health maintenance

Reconstitution steps

  1. Reconstitute in 2.5 mL bac water portions; inject slowly down vial wall.
  2. Swirl gently until dissolved. Final concentration: 2 mg/mL.
  3. Label with date; refrigerate 2–8 °C. Use within 28 days.

Supplies needed

10_day-week plan

  • 1 vial
  • 10 syringes
  • 2 mL bac water
  • 10 alcohol swabs
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Protocol overview & cycle notes

Normalize prostatic epithelial gene expression for cellular differentiation, anti-inflammatory signaling, and PSA secretion through the Prostamax tetrapeptide prostate bioregulator 10-day intensive course.

Off-cycle: 4–6 months between courses.

Storage & handling

Lyophilized: store below 25 °C. Reconstituted: refrigerate 2–8 °C; use within 28 days.

Injection & tracking tips

  • Inject subcutaneously at any time of day.
  • Monitor PSA levels before each 10-day course to track prostate health status.
  • Russian BPH protocols combine Prostamax with saw palmetto and alpha-blocker medication in integrative urology.

Tracking

Logging helps you and your provider spot patterns and adjust dose or timing.

  • IPSS (International Prostate Symptom Score) at baseline and 4 weeks post-course.
  • PSA at baseline and 3 months post-course.
  • Track urinary flow rate and post-void residual volume at baseline and 12 weeks.
Log your cycle in the calculator →

How this works & references

Prostamax (Lys-Asp-Glu-Leu) is a tetrapeptide bioregulator from Khavinson's group targeting prostatic epithelial tissue. Proposed mechanisms include normalization of androgen receptor expression, reduction of inflammatory cytokine gene transcription (IL-8, TNF-alpha) in prostate stromal cells, and restoration of differentiated secretory cell function. Russian clinical applications include BPH (benign prostatic hyperplasia) symptom reduction, chronic prostatitis support, and prostate cancer risk reduction as part of integrative oncology.

Sources

  • Source: Khavinson VK et al. — Short peptide bioregulators. Ann N Y Acad Sci. 2010;1207:66-75

Frequently asked questions

Can Prostamax be used if I have elevated PSA?
Elevated PSA requires urological evaluation to exclude prostate cancer before adding any peptide bioregulator. Prostamax is not a prostate cancer treatment. If elevated PSA has been investigated and benign etiology (BPH, prostatitis) confirmed, Prostamax may be appropriate as adjunct supportive therapy. Always with urologist supervision.
Does Prostamax affect testosterone levels?
No documented effect on testosterone levels in available Russian data. Prostamax targets intraprostatic gene expression, not systemic androgen production. It is not an anti-androgen and does not suppress testosterone like 5-alpha reductase inhibitors (finasteride, dutasteride).
Can Prostamax reduce BPH symptoms?
Russian practitioners report IPSS score improvements in BPH patients after Prostamax 10-day courses. The proposed mechanism — normalizing inflammatory gene expression and androgen receptor sensitivity in hyperplastic prostatic tissue — is consistent with BPH pathophysiology. Evidence level is anecdotal to case series; no RCT for Prostamax in BPH has been published.
Is Prostamax safe with alpha-blocker medications (tamsulosin)?
No pharmacokinetic interactions are expected — Prostamax is a peptide bioregulator, not a pharmacological receptor ligand. Tamsulosin blocks alpha-1 adrenergic receptors in the prostate and bladder neck for symptomatic relief; Prostamax targets gene expression. They can be used concurrently with physician oversight.
How long does Prostamax take to improve urinary symptoms?
Based on Russian clinical experience, urinary flow rate and IPSS improvements are typically noted 4–6 weeks after the 10-day Prostamax course — following the time required for gene expression normalization to manifest as structural and functional tissue improvements. Subsequent courses every 4–6 months maintain the gains.

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This content is for informational purposes only and does not constitute medical advice. Consult a licensed healthcare provider before starting any peptide therapy. Dosing and protocols may vary by formulation and prescriber.

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