MyPeptideMatchOverview
Semax is a synthetic analog of the ACTH (4-10) fragment with neuroprotective and cognitive effects. It is approved in Russia and Ukraine but not FDA-evaluated or approved in the US. There is no clear compounding pathway in the US. It has been studied for cognitive enhancement, neuroprotection, and stroke recovery, with moderate evidence from Russian clinical studies. US patients should not assume it is legally available; purchasing from overseas or unregulated sources carries legal and safety risks.
How It Works (Mechanism of Action)
Semax is thought to support neuroplasticity and neuroprotection through modulation of neurotrophic and neurotransmitter systems. Russian research has characterized mechanisms; US data are limited.
Primary Uses
Cognitive enhancement, neuroprotection, stroke recovery. Not FDA-approved in the US. Evidence moderate—Russian clinical studies.
FDA & Regulatory Status
Not FDA-approved. No clear compounding pathway in the US. Approved in Russia and Ukraine.
Last reviewed February 2026.
Clinical Evidence
Moderate—Russian clinical studies. Not evaluated by the FDA.
