MyPeptideMatch
Key Takeaways
- Typical Sermorelin dosing ranges from 100 mcg to 500 mcg daily, administered via subcutaneous injection.
- Titration schedules are important for optimizing efficacy and minimizing side effects.
- Medical supervision is crucial to adjust dosing based on individual factors such as body weight and treatment goals.
- Sermorelin is compounded under FDA Category 1, meaning it can be prescribed but is not FDA-approved for a specific indication.
What Is Sermorelin?
Sermorelin is a growth hormone-releasing hormone (GHRH) analog that stimulates the pituitary gland to produce growth hormone. It is primarily used in the context of anti-aging and growth hormone deficiency treatments. For more detailed information, visit the Sermorelin profile.
Standard Dosing Protocols
Sermorelin does not have an FDA-approved dosing regimen, as it is categorized as a compoundable substance under FDA Category 1. However, typical clinical practice involves a dosing range of 100 mcg to 500 mcg per day, administered subcutaneously. Some research protocols have utilized doses up to 1,000 mcg in divided doses for specific conditions (PMID 18046908).
Titration Schedules
Titration is a critical component of Sermorelin therapy, allowing gradual adjustment to optimize therapeutic outcomes while minimizing adverse effects. Initial dosing often starts at the lower end of the spectrum, around 100 mcg to 200 mcg daily, with incremental increases based on patient response and tolerability. Typically, adjustments may occur every 2-4 weeks, with close monitoring by healthcare providers (PMID 32257855).
Administration Method
Sermorelin is administered via subcutaneous injection, typically using a 29-31 gauge insulin syringe. Common injection sites include the abdomen, thigh, or upper arm. It is essential to rotate injection sites to prevent lipoatrophy. Reconstitution of Sermorelin is necessary, requiring mixing with bacteriostatic water and storage in a refrigerator to maintain potency (PMID 37806509).
