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Reviewed by MyPeptideMatch Editorial TeamLast reviewed February 2026Updated February 2026

CJC-1295 DAC Dosing Protocol: 5 mg Vial — Multi-Week Supply Guide

Extended CJC-1295 DAC supply from the 5 mg vial — provides 2–5 weeks of once-weekly 1–2 mg dosing from a single reconstitution.

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Quickstart highlights

CJC-1295 DAC with the Drug Affinity Complex maleimide modification produces serum half-life of 6–8 days via albumin binding, enabling once-weekly GHRH stimulation.

  • Concentration: 2 mg/mL (5 mg vial + 2.5 mL bacteriostatic water).
  • At 2 mg/mL: 1 mg = 50 units, 2 mg = 100 units once weekly.
  • One 5 mg vial covers 5 injections at 1 mg/week or 2.5 injections at 2 mg/week.
  • CJC-1295 DAC half-life: 6–8 days — once-weekly dosing is sufficient for therapeutic GH elevation.
  • Refrigerate; use within 28 days.

Dosing table

For educational reference only. Your prescribing provider may adjust doses based on your clinical profile and response.

WeekDose (µg)UnitsFrequencyNotes
1-4100050Once weekly1 mg — 50 units; 5 mg vial provides 5 weekly doses
5-122000100Once weekly2 mg — 100 units; 5 mg vial provides 2.5 weekly doses at this level

Reconstitution steps

  1. Draw 2.5 mL bacteriostatic water; inject slowly down the vial wall.
  2. Swirl gently until lyophilized powder dissolves; do not shake.
  3. Final concentration: 2 mg/mL. Label with date; refrigerate at 2–8 °C. Use within 28 days.
  4. Note: at 2 mg weekly dosing, one 5 mg vial provides 2 full injections plus one 1 mg partial — plan accordingly.

Supplies needed

8-week plan

  • 2 vials
  • 8 syringes
  • 5 mL bac water
  • 8 alcohol swabs

12-week plan

  • 3 vials
  • 12 syringes
  • 8 mL bac water
  • 12 alcohol swabs
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Protocol overview & cycle notes

Provide a multi-week CJC-1295 DAC supply from the efficient 5 mg vial for patients established on once-weekly 1–2 mg dosing protocols, minimizing reconstitution frequency.

Cycle length: 12 weeks on.

Off-cycle: 4–6 weeks off; measure IGF-1 before resuming.

Storage & handling

Lyophilized: store below 25 °C. Reconstituted at 2 mg/mL: refrigerate 2–8 °C; use within 28 days. At 1 mg weekly: one 5 mg vial covers 5 weekly injections. At 2 mg weekly: covers 2.5 weekly injections (less than 3 weeks).

Injection & tracking tips

  • CJC-1295 DAC's once-weekly dosing allows injection on any convenient day; maintain consistent weekly interval (±24 hours).
  • Combine with a daily GHRP (ipamorelin 200 µg at bedtime) for maximum GH axis activation while maintaining the convenient weekly DAC schedule.
  • The 5 mg vial is most efficient for 1 mg weekly dosing — provides 5 weeks from a single reconstitution.

Tracking

Logging helps you and your provider spot patterns and adjust dose or timing.

  • Measure IGF-1 at baseline, 4 weeks, and 8 weeks.
  • Track fasting glucose monthly — sustained GH elevation from DAC formulation may impair insulin sensitivity over time.
  • Monitor for carpal tunnel symptoms (wrist tingling) — a common early indicator of supraphysiological GH levels.
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How this works & references

CJC-1295 DAC with the Drug Affinity Complex maleimide modification produces serum half-life of 6–8 days via albumin binding, enabling once-weekly GHRH stimulation. The 5 mg vial at 2 mg/mL provides 5 weekly 1 mg doses or 2.5 weekly 2 mg doses from a single reconstitution event, improving sterility management over smaller vials.

Sources

Frequently asked questions

Is 2 mg weekly the correct dose for most patients?
2 mg weekly is the most commonly used CJC-1295 DAC dose in compounding protocols. The Teichman trial used weight-based dosing (30–60 µg/kg); for a 70 kg adult, that ranges from 2.1–4.2 mg weekly. Most protocols cap at 2 mg to balance efficacy with manageable IGF-1 elevation.
Can I use the 5 mg vial for twice-weekly dosing?
At 2 mg 2x weekly (4 mg/week total), one 5 mg vial provides slightly more than one week's supply. At this frequency and dose, 5 mg vials require weekly reconstitution — the 10 mg vial would be more practical for twice-weekly protocols.
How does IGF-1 track week-by-week with CJC-1295 DAC?
IGF-1 rises progressively: +20–30% above baseline after the first injection, +35–60% by week 4, plateauing at +50–80% above baseline by 8–12 weeks with continued once-weekly dosing.
What happens to GH secretion during the off-cycle?
After stopping CJC-1295 DAC, IGF-1 declines to near-baseline within 2–4 weeks as the albumin-bound peptide clears. Endogenous GH secretion returns to pre-treatment patterns. No rebound suppression occurs, unlike exogenous HGH withdrawal.
Do I need to keep the 5 mg vial cold immediately after reconstitution?
Yes — refrigerate immediately after reconstitution (2–8 °C). Do not leave at room temperature for more than 2 hours. CJC-1295 DAC degrades faster in solution than lyophilized; proper cold storage is critical for maintaining potency over the 28-day window.

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This content is for informational purposes only and does not constitute medical advice. Consult a licensed healthcare provider before starting any peptide therapy. Dosing and protocols may vary by formulation and prescriber.

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