MyPeptideMatchCJC-1295 No DAC Dosing Protocol: 5 mg Vial — Pulsatile GHRH Dosing Guide
CJC-1295 without DAC (Modified GRF 1-29) protocol — the pulsatile GHRH analogue for 2–3x daily injection alongside GHRPs.
Quickstart highlights
CJC-1295 without DAC (also called Modified GRF 1-29 or Mod-GRF) is a 29-amino acid GHRH analogue with four amino acid substitutions (Ala8, Glu15, Ala18, Arg26) that improve receptor affinity and proteolytic stability over native GHRH while maintaining a physiological 30-minute half-life.
- Concentration: 2 mg/mL (5 mg vial + 2.5 mL bacteriostatic water).
- At 2 mg/mL: 200 µg = 10 units, 300 µg = 15 units per injection.
- Half-life: ~30 minutes — inject simultaneously with GHRP (ipamorelin, GHRP-2) for synergistic GH release.
- Can be mixed with ipamorelin or GHRP-2 in the same syringe immediately before injection.
- One 5 mg vial provides ~17 doses at 300 µg — approximately 5–6 days at 3x daily.
Dosing table
For educational reference only. Your prescribing provider may adjust doses based on your clinical profile and response.
| Week | Dose (µg) | Units | Frequency | Notes |
|---|---|---|---|---|
| 1-4 | 200 | 10 | 1–2x daily with GHRP | 200 µg — 10 units; pair with ipamorelin or GHRP-2 (200 µg) in same syringe or adjacent site |
| 5-12 | 300 | 15 | 2–3x daily with GHRP | 300 µg — 15 units; 3x daily protocol produces maximum pulsatile GH output |
Reconstitution steps
- Draw 2.5 mL bacteriostatic water; inject slowly down the vial wall.
- Swirl gently until powder dissolves; do not shake.
- Final concentration: 2 mg/mL (2,000 µg/mL). At 2 mg/mL: 200 µg = 10 units, 300 µg = 15 units.
- Label with date; refrigerate at 2–8 °C. Use within 28 days.
Supplies needed
4-week plan
- 2 vials
- 28 syringes
- 5 mL bac water
- 28 alcohol swabs
8-week plan
- 4 vials
- 56 syringes
- 10 mL bac water
- 56 alcohol swabs
12-week plan
- 5 vials
- 84 syringes
- 13 mL bac water
- 84 alcohol swabs
Protocol overview & cycle notes
Achieve maximal pulsatile GH secretion through the precise co-injection of CJC-1295 No DAC (GHRH) and a GHRP (ipamorelin or GHRP-2) 2–3x daily, mimicking the natural GHRH + ghrelin synergy that drives physiological GH pulses.
Cycle length: 12 weeks on.
Off-cycle: 4–6 weeks off; measure IGF-1 before resuming.
Storage & handling
Injection & tracking tips
- CJC-1295 No DAC has a 30-minute half-life — timing with the GHRP injection is critical; inject within 5 minutes of each other.
- Can be mixed in the same syringe as ipamorelin or GHRP-2 for a single injection — stable when mixed immediately before use; do not pre-mix and store.
- Inject in fasted state (2+ hours post-meal); food-driven insulin blunts GH response to the peptide combination.
Tracking
Logging helps you and your provider spot patterns and adjust dose or timing.
- Measure IGF-1 at baseline, 6 weeks, and 12 weeks.
- Track sleep quality nightly (subjective 0–10 or wearable deep sleep data).
- Log body fat percentage monthly via InBody or DEXA.
How this works & references
Sources
- Source: Bowers CY — Unnatural GH-releasing peptides beget natural ghrelin. J Clin Endocrinol Metab. 2001
- Source: Ghigo E et al. — GH-releasing peptide-6: hypothalamic or pituitary site of action? J Clin Endocrinol Metab. 1993
- Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. Teichman SL et al. — J Clin Endocrinol Metab — 2006
- Activation of the GH/IGF-1 axis by CJC-1295, a long-acting GHRH analog, results in serum protein profile changes in normal adult subjects. Sackmann-Sala L et al. — Growth Horm IGF Res — 2009
Frequently asked questions
What is the key difference between CJC-1295 DAC and CJC-1295 No DAC?
Can I mix CJC-1295 No DAC with ipamorelin in one syringe?
Why does the No DAC formulation produce more physiological GH pulsatility?
Is CJC-1295 No DAC the same as Mod-GRF 1-29?
How long before results are noticeable with the No DAC + ipamorelin combination?
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View protocolThis content is for informational purposes only and does not constitute medical advice. Consult a licensed healthcare provider before starting any peptide therapy. Dosing and protocols may vary by formulation and prescriber.