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Reviewed by MyPeptideMatch Editorial TeamLast reviewed February 2026Updated February 2026

GHRP-6 Dosing Protocol: 5 mg Vial — Full Cycle Dosing Schedule & Supplies

Complete GHRP-6 dosing protocol using the 5 mg vial, covering full 4–12 week GH secretagogue cycles with supplies checklist.

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Quickstart highlights

GHRP-6 was among the first synthetic GHRPs studied in humans (Bowers et al., 1984).

  • Concentration: 2 mg/mL (5 mg vial + 2.5 mL bacteriostatic water).
  • At 2 mg/mL: 200 µg = 10 units, 300 µg = 15 units per injection.
  • GHRP-6 causes significant hunger within 30 minutes — the strongest appetite effect among GHRPs.
  • At 300 µg 3x daily, one 5 mg vial lasts ~5–6 days; plan 15+ vials for a 12-week cycle.
  • Combine with CJC-1295 No DAC for 2–4x greater GH output.

Dosing table

For educational reference only. Your prescribing provider may adjust doses based on your clinical profile and response.

WeekDose (µg)UnitsFrequencyNotes
1-4200102x daily (fasted)200 µg — 10 units; 5 mg vial provides 25 doses (~12 days at 2x daily)
5-12300152–3x daily (fasted)300 µg — 15 units; 17 doses per vial (~8 days at 2x daily, 5–6 days at 3x daily)

Reconstitution steps

  1. Draw 2.5 mL bacteriostatic water; inject slowly down vial wall.
  2. Swirl gently until dissolved; do not shake.
  3. Final concentration: 2 mg/mL. Label with date; refrigerate at 2–8 °C. Use within 28 days.

Supplies needed

4-week plan

  • 1 vial
  • 28 syringes
  • 3 mL bac water
  • 28 alcohol swabs

8-week plan

  • 3 vials
  • 56 syringes
  • 8 mL bac water
  • 56 alcohol swabs

12-week plan

  • 5 vials
  • 84 syringes
  • 13 mL bac water
  • 84 alcohol swabs
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Protocol overview & cycle notes

Stimulate robust GH secretion and leverage GHRP-6's appetite-stimulating properties using the 5 mg vial for full 4–12 week cycles, particularly suitable for patients seeking concurrent GH-mediated anabolism and appetite enhancement.

Cycle length: 12 weeks on.

Off-cycle: 4–6 weeks off after every 12-week cycle; monitor morning cortisol.

Storage & handling

Lyophilized: store below 25 °C. Reconstituted at 2 mg/mL: refrigerate 2–8 °C; use within 28 days. At 300 µg 3x daily, one 5 mg vial lasts approximately 5–6 days — plan 15+ vials for a full 12-week cycle at max frequency.

Injection & tracking tips

  • Inject immediately before planned meals to leverage GHRP-6's appetite-stimulating effect for caloric intake.
  • Do not inject GHRP-6 if already full — food at injection time suppresses GH response by up to 50%.
  • Combine with CJC-1295 No DAC for synergistic GH release; inject both from the same syringe or adjacent sites simultaneously.

Tracking

Logging helps you and your provider spot patterns and adjust dose or timing.

  • Track appetite and meal caloric intake for the first 4 weeks — GHRP-6 is sometimes used to increase caloric intake in underweight individuals.
  • Measure IGF-1 at baseline and 6 weeks.
  • Monitor morning cortisol monthly; GHRP-6 at 300 µg can elevate cortisol by 20–40%.
Log your cycle in the calculator →

How this works & references

GHRP-6 was among the first synthetic GHRPs studied in humans (Bowers et al., 1984). It activates the GHSR-1a ghrelin receptor with high affinity, producing GH spikes of 4–8 ng/mL at 200 µg doses in young adults and 2–4 ng/mL in older adults. The marked hunger response is partially mediated through vagal gastric afferents and NPY/AgRP neurons. Combining GHRP-6 (200–300 µg) with CJC-1295 No DAC (200–300 µg) produces synergistic GH spikes of 10–20 ng/mL.

Sources

Frequently asked questions

What distinguishes GHRP-6 from GHRP-2 for muscle building?
GHRP-6 produces comparable GH pulse amplitudes to GHRP-2 but with stronger appetite stimulation. For lean gaining protocols where caloric surplus is desired, GHRP-6 provides both GH secretagogue activity and appetite support. For cutting or body recomposition, GHRP-2 or ipamorelin is preferred.
How much does GHRP-6 raise IGF-1?
At 200 µg 2x daily combined with CJC-1295 No DAC (300 µg), IGF-1 typically rises 40–80 ng/mL above baseline after 6–8 weeks. GHRP-6 monotherapy raises IGF-1 by 20–40 ng/mL over the same period.
Is GHRP-6 appropriate for women?
Yes — GHRP-6 has been studied in both sexes. Women may be more sensitive to hunger effects at equivalent doses. Starting at 100 µg 1–2x daily and assessing tolerance before advancing to 200 µg is recommended for female patients.
Can I use GHRP-6 if I have GI issues?
GHRP-6 stimulates gastric motility and can worsen symptoms of IBS or acid reflux at doses ≥200 µg. Patients with pre-existing GI conditions may prefer ipamorelin, which does not stimulate gastric motility.
Does GHRP-6 need to be refrigerated after reconstitution?
Yes — always refrigerate at 2–8 °C after reconstitution and use within 28 days. Never freeze. Let the vial come to room temperature (5–10 minutes) before drawing a dose to minimize cold-induced injection discomfort.

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This content is for informational purposes only and does not constitute medical advice. Consult a licensed healthcare provider before starting any peptide therapy. Dosing and protocols may vary by formulation and prescriber.

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