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Reviewed by MyPeptideMatch Editorial TeamLast reviewed February 2026Updated February 2026

Ipamorelin Dosing Protocol: 10 mg Vial — Extended Supply Dosing Guide

Multi-week ipamorelin supply from the 10 mg vial — ideal for patients on established 300 µg once-to-three-daily protocols.

Quickstart highlights

Ipamorelin's selectivity for GHSR-1a over ACTH and prolactin axes enables high-frequency dosing without the adrenal side effects of other GHRPs.

  • Concentration: 2 mg/mL (10 mg vial + 5 mL bacteriostatic water).
  • At 2 mg/mL: 200 µg = 10 units, 300 µg = 15 units per injection.
  • One 10 mg vial provides 33 doses at 300 µg or 11 days at 300 µg 3x daily.
  • Best for 2–3x daily protocols; reduces reconstitution frequency vs. 5 mg vials.
  • Refrigerate; use within 28 days.

Dosing table

For educational reference only. Your prescribing provider may adjust doses based on your clinical profile and response.

WeekDose (µg)UnitsFrequencyNotes
1-420010Once daily (before bed)200 µg nightly — 10 units; 10 mg vial provides 50 nightly doses
5-12300151–3x daily300 µg per injection; 33 doses at this level per vial
13+300153x dailyThree 300 µg injections daily — morning, pre-workout, bedtime; 11 days per vial at 3x daily

Reconstitution steps

  1. Draw 5 mL bacteriostatic water (two 2.5 mL draws from a 3 mL syringe); inject slowly down the vial wall.
  2. Swirl gently until powder fully dissolves; do not shake.
  3. Final concentration: 2 mg/mL. Label with date; refrigerate at 2–8 °C. Use within 28 days.

Supplies needed

12-week plan

  • 1 vial
  • 84 syringes
  • 5 mL bac water
  • 84 alcohol swabs

12_3xdaily-week plan

  • 3 vials
  • 252 syringes
  • 15 mL bac water
  • 252 alcohol swabs
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Protocol overview & cycle notes

Provide an extended multi-week supply of ipamorelin from the 10 mg vial for patients on high-frequency (2–3x daily) dosing protocols, optimizing cost and minimizing reconstitution events.

Cycle length: 12 weeks on.

Off-cycle: 4 weeks off; measure IGF-1 before restarting.

Storage & handling

Lyophilized: store below 25 °C. Reconstituted at 2 mg/mL: refrigerate 2–8 °C; use within 28 days. At 300 µg 3x daily, one 10 mg vial lasts approximately 11 days; plan 3+ vials per 12-week cycle.

Injection & tracking tips

  • For the 3x-daily protocol, inject 30–60 minutes pre-workout (mid-day or afternoon), once more in the morning, and once before bed.
  • Always inject in fasted state or 2+ hours post-meal.
  • The 10 mg vial is most efficient for patients at 300 µg 3x daily or higher — reduces reconstitution frequency versus the 5 mg vial.

Tracking

Logging helps you and your provider spot patterns and adjust dose or timing.

  • Measure IGF-1 at baseline, 6 weeks, and 12 weeks.
  • Track lean mass and body fat via body composition scale or DEXA every 8 weeks.
  • Log resting morning cortisol if using high-frequency dosing (3x daily) to confirm ipamorelin selectivity.
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How this works & references

Ipamorelin's selectivity for GHSR-1a over ACTH and prolactin axes enables high-frequency dosing without the adrenal side effects of other GHRPs. Three daily injections of 300 µg produce near-continuous GH pulse stimulation, maximizing somatotroph output while preserving feedback regulation. Hansen et al. (1999) demonstrated dose-dependent GH release with peak serum GH at 15–30 minutes post-injection and return to baseline within 3 hours.

Frequently asked questions

How many 10 mg vials do I need for a 12-week cycle at 300 µg 3x daily?
At 300 µg × 3 doses/day × 84 days = 75.6 mg total; 10 mg/vial ÷ 10 mg = 7.56 — approximately 8 vials for a full 12-week 3x-daily cycle.
Is 3x-daily ipamorelin significantly better than once-daily?
For body composition, 3x-daily generates higher cumulative GH pulse area under the curve, leading to greater IGF-1 elevation (+50–80 ng/mL vs. +20–40 ng/mL with once-daily). However, results plateau with time; many practitioners use 2x-daily as the optimal balance between efficacy and cost.
Can I mix ipamorelin and CJC-1295 in the same syringe?
Yes — ipamorelin and CJC-1295 No DAC can be drawn into the same syringe and injected at a single site. The combination is stable when mixed immediately before injection. Do not pre-mix and store.
What blood tests should I monitor?
IGF-1 (baseline and every 6 weeks), fasting glucose (monthly at 3x daily dosing), and optional resting cortisol (to confirm ipamorelin selectivity versus cortisol-elevating GHRPs). Liver enzymes and lipid panel every 12 weeks if on long-term protocol.
Does ipamorelin cause gynecomastia?
Unlike GHRP-6, ipamorelin does not significantly elevate prolactin — the primary driver of GHRP-induced gynecomastia risk. GH itself can cause mild gynecomastia at supraphysiological levels, but this is rarely reported with ipamorelin protocols at the doses described.

Related protocols

This content is for informational purposes only and does not constitute medical advice. Consult a licensed healthcare provider before starting any peptide therapy. Dosing and protocols may vary by formulation and prescriber.