What Is Peptide Therapy? A Complete Beginner's Guide (2026)
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MyPeptideMatch Team
·9 min read
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Key Takeaways
Peptide therapy uses short chains of amino acids to support health goals such as weight loss, recovery, and anti-aging.
Some peptides are FDA-approved (e.g., semaglutide, tirzepatide); others are only legally available in certain forms or not at all.
Peptide therapy is offered by licensed providers and compounding pharmacies where legally permitted.
Costs and access depend on the peptide, your location, and whether you use insurance or cash-based programs.
If you’ve been curious about what peptide therapy is, you’re not alone. Peptides are short chains of amino acids that can influence everything from metabolism and appetite to tissue repair and hormone release. In this guide we’ll cover the basics: what peptides are, how peptide therapy works, who typically offers it, and what you can expect from a first visit. We’ll also touch on cost, safety, and how to use our clinic directory to find a provider.
What Are Peptides?
Peptides are short chains of amino acids—the building blocks of proteins. They occur naturally in the body and can also be made in the lab. Many hormones and signaling molecules are peptides (e.g., insulin, GLP-1). In “peptide therapy,” we usually mean therapeutic peptides that are used to support specific health goals, such as:
Skin and anti-aging (e.g., GHK-Cu when used topically)
So what is peptide therapy? In practice, it’s the use of these compounds—usually by injection, sometimes oral or topical—under the care of a licensed provider, where legally available.
How Peptide Therapy Works
Different peptides work in different ways. GLP-1 agonists (e.g., semaglutide, tirzepatide) reduce appetite and improve blood sugar. Growth hormone–releasing peptides (e.g., sermorelin) stimulate your pituitary to release more growth hormone. Topical copper peptides (e.g., GHK-Cu) support skin and wound healing when used in approved formulations. Your provider will choose (or avoid) specific peptides based on your goals, health history, and current FDA and compounding rules—which vary by compound.
Who Offers Peptide Therapy?
Peptide therapy is offered by physicians, nurse practitioners, and other licensed providers who prescribe FDA-approved peptides (e.g., Ozempic, Wegovy, Vyleesi) or work with licensed compounding pharmacies where a peptide is legally compoundable (e.g., sermorelin, topical GHK-Cu). Not every peptide can be legally prescribed or compounded in the US; our Peptide Encyclopedia explains the status of each. You can browse our directory to find clinics that offer peptide therapy in your area.
What to Expect at a First Visit
A first visit usually includes a review of your health history, goals, and any contraindications. The provider will explain which options are appropriate and legal. If a peptide is prescribed, you may receive it as an injection (often at home after training), an oral medication, or a topical product. Follow-up and sometimes labs are used to monitor response and safety. Length of treatment depends on the peptide and your goals.
Cost and Insurance
Cost varies widely. FDA-approved brand names (e.g., Ozempic, Wegovy) can be $900–$1,400+ per month without insurance; many plans now cover them for diabetes or obesity. Compounded peptides (when legal) are often $200–$500+ per month and are usually cash-based. Insurance rarely covers elective or off-label peptide use. HSA/FSA can often be used when a peptide is prescribed for a qualifying purpose.
Safety and Regulation
Safety depends on the peptide and how it’s obtained. FDA-approved products have rigorous data; compounded products must come from licensed pharmacies. Some peptides are prohibited for compounding or not approved at all—using them can be unsafe and illegal. Our encyclopedia and blog posts on safety and FDA regulations go deeper.
Bottom Line
Peptide therapy is the use of therapeutic peptides under medical supervision where legally permitted. It can support weight loss, recovery, anti-aging, and other goals when the right peptide is chosen and obtained through the right channels. Use our clinic directory and Peptide Encyclopedia to learn more and find a provider near you.
Find a Peptide Therapy Clinic Near You
Browse our directory of verified peptide therapy clinics across the United States. Compare providers, read reviews, and request a consultation.
MyPeptideMatch.com does not provide medical advice. Always consult a qualified healthcare provider before starting any peptide therapy. Regulatory status may change.