


NRI Integrative Health & Aesthetics, established in 2010 in Indianapolis, Indiana, provides comprehensive integrative medicine services under the clinical direction of Nichole Ingersoll, FNP-BC, who holds certifications from the American Nurses Credentialing Center (ANCC), American Association of Nurse Practitioners (AANP), and is an AAI Certified Master Aesthetics Injector. The practice addresses complex chronic conditions through functional medicine approaches that combine hormone optimization, peptide therapy, gut health restoration, thyroid management, autoimmune disease treatment, mental health support, and medical weight loss alongside aesthetic medicine services. Patients throughout Indianapolis and central Indiana access care through both in-person consultations at the clinic and telehealth appointments for Indiana residents seeking ongoing management of chronic conditions.
NRI Integrative Health & Aesthetics - Indianapolis, IN offers an extensive peptide therapy program with 27 different peptides available, including metabolic peptides including AOD-9604, Liraglutide, growth hormone secretagogues like CJC-1295, and other specialized compounds. Treatment selection is individualized based on comprehensive health assessments and patient goals.
Nichole Ingersoll brings over a decade of experience in integrative and functional medicine to her Indianapolis practice, combining her nurse practitioner training with advanced certifications in aesthetics and functional approaches to chronic disease. Her clinical methodology emphasizes identifying root causes of symptoms through comprehensive laboratory testing including thyroid panels with reverse T3, sex hormone assessments, cortisol patterns, comprehensive metabolic panels, inflammatory markers, and gut health evaluations including microbiome analysis when indicated. Patients with autoimmune conditions receive detailed assessments of immune function, food sensitivities, and environmental triggers, while those seeking hormone optimization undergo thorough evaluation of estrogen, progesterone, testosterone, DHEA, and thyroid function before beginning bioidentical hormone replacement or peptide protocols. The practice addresses mental health concerns through an integrative lens, examining the connections between hormone imbalances, gut dysbiosis, nutrient deficiencies, and mood disorders rather than treating psychiatric symptoms in isolation.
New patients at NRI Integrative Health & Aesthetics begin with extended initial consultations that review complete health histories, current symptoms, previous treatments, and comprehensive laboratory testing to establish baseline function across endocrine, metabolic, immune, and gastrointestinal systems. Nichole Ingersoll develops individualized treatment protocols that may combine bioidentical hormone replacement, peptide therapy, pharmaceutical interventions when necessary, targeted nutritional supplementation, dietary modifications, and lifestyle interventions based on each patient's specific laboratory findings and clinical presentation. Follow-up visits track symptom resolution, monitor laboratory markers, and adjust treatment protocols as patients progress through different phases of healing. The clinic maintains a 4.7-star rating from patient reviews, with individuals noting the thoroughness of initial evaluations, the time spent explaining test results and treatment rationales, and the integration of multiple therapeutic modalities to address complex chronic conditions.
The Indianapolis clinic serves patients seeking alternatives to conventional symptom management for conditions including hypothyroidism, adrenal dysfunction, perimenopause and menopause, andropause, polycystic ovary syndrome, insulin resistance, small intestinal bacterial overgrowth, leaky gut syndrome, rheumatoid arthritis, lupus, chronic Lyme disease, fibromyalgia, and treatment-resistant depression or anxiety. Telehealth services allow Indiana residents throughout the state to access Nichole Ingersoll's expertise in functional medicine and peptide therapy without traveling to Indianapolis for every appointment, though initial consultations and certain follow-ups requiring physical examination or aesthetic procedures occur in person. The practice's combination of medical weight loss programs, aesthetic services including advanced injectables, and comprehensive chronic disease management allows patients to address both functional health optimization and aesthetic concerns within a single clinical relationship, with all services informed by the same integrative medicine philosophy that prioritizes identifying and treating underlying physiological imbalances.
Nichole Ingersoll· FNP-BC
Nichole Ingersoll, RN, MSN, FNP-BC
Owner & Medical Director
A graduate of both Indiana University and University of Indianapolis, Nichole has over 22 years of Family Practice experience, with the last 17 years focusing on integrative medicine, with a blend of traditional and functional medicine. Utilizing integrative medicine therapies Nichole has been blessed to be able to help so many of her patients, as well as herself and her family. Nichole has been employed as adjunct faculty at the University of Indianapolis and has been involved in many speaking engagements around the Midwest.
Lori Rigney, RN, MSN, FNP-C
Family Nurse Practitioner & Functional Medicine Provider
Lori received her undergraduate and graduate degrees from Ball State University. She is an experienced integrative Nurse Practitioner who specializes in women’s health, hormones, thyroid disorders, gut health, weight loss, autoimmune disorders, and aesthetic medicine. Lori partners with you to educate, motivate, and advocate to help you achieve your health goals.
Integrative Medical Services
Primary Care, Peptide Therapy, Hormone & Thyroid Management, Insulin Resistance, Continuous Glucose Monitoring, Weight Loss, Advanced Testing, IV Therapy, Targeted Nutrient Therapy, Anti-Aging Regenerative Health, Nutrient Injections (B12, MIC/B12 etc).
Functional Medicine
Bio Identical Hormone Replacement, Hormone Pellet Therapy, Creams/Drops/Troches, Shots, Hormone Replacement, Physician Grade Supplements & Products.
Aesthetic Services
Botox/Dysport/Xeomin, InstaLift Threads, Advanced Filler Techniques, Titan Laser Treatments, IPL Laser Complexion Treatments, PRP Facials, Diamond Glow, Medical Grade Skin Care.
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